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Drug Information

Drug Information for ZEBUTAL™ CAPSULES BRAND OF BUTALBITAL, ACETAMINOPHEN, AND CAFFEINE CAPSULES, USP (FIRST HORIZON PHARMACEUTICAL CORPORATION): DESCRIPTION

ZEBUTAL™ Capsules brand of Butalbital, Acetaminophen, and Caffeine is supplied in capsule form for oral administration. Each ZEBUTAL™ Capsule contains:
- Butalbital, USP...........................................50 mg
- Acetaminophen, USP...............................500 mg
- Caffeine, USP.............................................40 mg
In addition, each capsule contains the following inactive ingredients: Colloidal Silicon Dioxide, Magnesium Stearate, Sodium Lauryl Sulfate, and Sodium Starch Glycolate.
Capsule shell contains: D&C Red #33, D&C Yellow #10, FD&C Red #40, Gelatin and Titanium Dioxide. The imprinting ink contains Titanium Dioxide.
Butalbital (5-allyl-5-isobutylbarbituric acid), a white, odorless, crystalline powder having a slightly bitter taste, is a short to intermediate-acting barbiturate. It has the following structural formula:
Acetaminophen (4'-hydroxyacetanilide), a slightly bitter, white, odorless, crystalline powder, is a non-opiate, non-salicylate analgesic and antipyretic. It has the following structural formula:
Caffeine (1,3,7,-trimethylxanthine), a bitter, white crystalline powder or white-glistening needles, is a central nervous system stimulant. It has the following structural formula:

Drug Information Provided by National Library of Medicine (NLM).

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