- Differential Diagnosis
- Try building your search one term at a time, and be as specific as you can! Search term example: "chronic cough".
- Do not enter multiple findings such as "anemia, chronic cough, weight loss, vomiting" all at the same time.
- After selecting your term from the search results a list of possible diagnoses will be generated. If the list is too long, you will be able to narrow it down by entering additional terms.
- Do not enter values such as "heart rhythm 110" or "sodium 125", instead use "tachycardia" or "hyponatremia".
Drug Information for TRIAMTERENE/HYDROCHLOROTHIAZIDECAPSULES, USP37.5 MG/25 MG (BARR LABORATORIES, INC.): DESCRIPTION
- CLINICAL PHARMACOLOGY
- INDICATIONS AND USAGE
- ADVERSE REACTIONS
- DOSAGE AND ADMINISTRATION
- HOW SUPPLIED
- External Links Related to TRIAMTERENE/HYDROCHLOROTHIAZIDECAPSULES, USP37.5 MG/25 MG (BARR LABORATORIES, INC.)
Triamterene is an antikaliuretic agent and hydrochlorothiazide is a diuretic/antihypertensive agent.
At 50°C, triamterene is practically insoluble in water (less than 0.1%). It is soluble in formic acid, sparingly soluble in methoxyethanol and very slightly soluble in alcohol.
Triamterene is 2,4,7-triamino-6-phenylpteridine and its structural formula is:
Hydrochlorothiazide is slightly soluble in water. It is soluble in dilute ammonia, dilute aqueous sodium hydroxide and dimethylformamide. It is sparingly soluble in methanol.
Hydrochlorothiazide is 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7- sulfonamide 1,1-dioxide and its structural formula is:
Each capsule, for oral administration, contains 37.5 mg triamterene and 25 mg hydrochlorothiazide. In addition, inactive ingredients include cetylpyridinium chloride, gelatin, lactose monohydrate, magnesium stearate, microcrystalline cellulose, polysorbate 80, pregelatinized starch, sodium starch glycolate and titanium dioxide.
This product complies with USP Dissolution Test 3.
- Drug Information Provided by National Library of Medicine (NLM).