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Drug Information for TOLMETIN SODIUM CAPSULES, USP (Mylan Pharmaceuticals Inc.): DESCRIPTION
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Each capsule for oral administration contains 492 mg of tolmetin sodium, USP as the dihydrate in an amount equivalent to 400 mg of tolmetin. Each capsule contains 36 mg (1.568 mEq) of sodium and the following inactive ingredients: FD&C Blue #1, colloidal silicon dioxide, croscarmellose sodium, gelatin, magnesium stearate, microcrystalline cellulose, sodium lauryl sulfate and titanium dioxide.
The pKa of tolmetin is 3.5 and tolmetin sodium is freely soluble in water. Tolmetin sodium is a non-steroidal anti-inflammatory agent. The structural formula is:

(C15H14NNaO3 • 2H2O) M.W. 315.30
Sodium 1-methyl-5 p-toluoylpyrrole-2-acetate dihydrate.
- Drug Information Provided by National Library of Medicine (NLM).