Drug Information for LORAZEPAM TABLETS, USP CIV 40-8993 Revised – August 2007Rx only (Actavis Elizabeth LLC): DOSAGE AND ADMINISTRATION

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  • Lorazepam is administered orally. For optimal results, dose, frequency of administration, and duration of therapy should be individualized according to patient response. To facilitate this 0.5 mg, 1 mg, and 2 mg tablets are available.

    The usual range is 2 to 6 mg/day given in divided doses, the largest dose being taken before bedtime, but the daily dosage may vary from 1 to 10 mg/day.

    For anxiety, most patients require an initial dose of 2 to 3 mg/day given b.i.d. or t.i.d.

    For insomnia due to anxiety or transient situational stress, a single daily dose of 2 to 4 mg may be given, usually at bedtime.

    For elderly or debilitated patients, an initial dosage of 1 to 2 mg/day in divided doses is recommended to be adjusted as needed and tolerated.

    The dosage of lorazepam should be increased gradually when needed to help avoid adverse effects. When higher dosage is indicted, the evening dose should be increased before the daytime doses.

  • Drug Information Provided by National Library of Medicine (NLM).