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Drug Information for LISINOPRIL (Apotex Corp.): DESCRIPTION
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Lisinopril is an oral long-acting angiotensin converting enzyme inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-carboxy-3-phenyl-propyl)-L-lysyl]-L-proline dihydrate. Its molecular formula is C21H31N3O5·2H2O and its structural formula is:
Lisinopril is a white, crystalline powder, with a molecular weight of 441.52. It is soluble in water and sparingly soluble in methanol and practically insoluble in acetone and ethanol.
Each tablet, for oral administration, contains 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg or 40 mg of lisinopril. In addition, each tablet contains the following inactive ingredients:
2.5 mg tablets - anhydrous lactose, magnesium stearate.
5, 10, 20 and 30 mg tablets - anhydrous lactose, ferric oxide red shade, magnesium stearate
40 mg tablets - anhydrous lactose, ferric oxide yellow shade, magnesium stearate.
- Drug Information Provided by National Library of Medicine (NLM).