Drug Information for LISINOPRIL (Apotex Corp.): DESCRIPTION

  • Lisinopril is an oral long-acting angiotensin converting enzyme inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-carboxy-3-phenyl-propyl)-L-lysyl]-L-proline dihydrate. Its molecular formula is C21H31N3O5·2H2O and its structural formula is:

    Lisinopril is a white, crystalline powder, with a molecular weight of 441.52. It is soluble in water and sparingly soluble in methanol and practically insoluble in acetone and ethanol.

    Each tablet, for oral administration, contains 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg or 40 mg of lisinopril. In addition, each tablet contains the following inactive ingredients:

    2.5 mg tablets - anhydrous lactose, magnesium stearate.

    5, 10, 20 and 30 mg tablets - anhydrous lactose, ferric oxide red shade, magnesium stearate

    40 mg tablets - anhydrous lactose, ferric oxide yellow shade, magnesium stearate.

  • Drug Information Provided by National Library of Medicine (NLM).