- Differential Diagnosis
Drug Information for Histamine Phosphate (ALK-Abello, Inc.): OVERDOSAGE
- CLINICAL PHARMACOLOGY
- INDICATIONS AND USAGE
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- HOW SUPPLIED
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A large subcutaneous dose of Histamine Phosphate may cause severe occipital headache, blurred vision, anginal pain, a rapid drop in blood pressure, and cyanosis of the face. Overdosage may cause severe symptoms including vasomotor collapse, shock, and even death.
Epinephrine Injection 0.01 mg/kg to a maximum of 1.0 mg given subcutaneously or intramuscularly should be used in case of emergency due to severe reactions (see Precautions). An antihistamine preparation may be given intramuscularly to ameliorate systemic reaction to overdose.
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