Drug Information for HALOBETASOL PROPIONATE CREAM, 0.05% (Perrigo Israel Pharmaceuticals Ltd.): DESCRIPTION

  • Halobetasol propionate cream, 0.05% contains halobetasol propionate, a synthetic corticosteroid for topical dermatological use. The corticosteroids constitute a class of primarily synthetic steroids used topically as an anti-inflammatory and antipruritic agent.

    Chemically halobetasol propionate is 21-chloro-6α, 9-difluoro=11β, 17-dihydroxy-16β-methylpregna-1, 4-diene-3-20-dione, 17-propionate, C25H31ClF2O5. It has the following structural formula:

    Halobetasol propionate has the molecular weight of 485. It is a white crystalline powder insoluble in water.

    Each gram of halobetasol propionate cream, 0.05% contains 0.5 mg of halobetasol propionate in a cream base of cetyl alcohol, diazolidinyl urea, glycerin, isopropyl isostearate, isopropyl palmitate, methylchloroisothiazolinone, (and) methylisothiazolinone, steareth-21 and water.

  • Drug Information Provided by National Library of Medicine (NLM).