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Drug Information for GLIPIZIDE TABLETS USPFor Oral UseRx only (Ivax Pharmaceuticals, Inc.): DESCRIPTION
- INDICATIONS AND USAGE
- ADVERSE REACTIONS
- DOSAGE AND ADMINISTRATION
- HOW SUPPLIED
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Glipizide tablets USP are oral blood-glucose-lowering drugs of the sulfonylurea class.
The Chemical Abstracts name of glipizide is 1-cyclo-hexyl-3-[[p-[2-(5-methylpyrazine- carboxamido) ethyl]-phenyl]sulfonyl]urea. The molecular formula is C21H27N5O4S; the molecular weight is 445.55; the structural formula is shown below:
Glipizide is a whitish, odorless powder with a pKa of 5.9. It is insoluble in water and alcohols, but soluble in 0.1 N NaOH; it is freely soluble in dimethylformamide. Glipizide tablets for oral use are available in 5 and 10 mg strengths.
Each tablet contains the following inactive ingredients: silicon dioxide; lactose monohydrate; microcrystalline cellulose; pregelatinized starch; stearic acid.
- Drug Information Provided by National Library of Medicine (NLM).