Drug Information for Enalapril Maleate Tablets, USP (Sandoz Inc.): Hepatic Failure

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  • Rarely, ACE inhibitors have been associated with a syndrome that starts with cholestatic jaundice and progresses to fulminant hepatic necrosis, and (sometimes) death. The mechanism of this syndrome is not understood. Patients receiving ACE inhibitors who develop jaundice or marked elevations of hepatic enzymes should discontinue the ACE inhibitor and receive appropriate medical follow-up.

  • Drug Information Provided by National Library of Medicine (NLM).
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