- Differential Diagnosis
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Drug Information for DIAZEPAM ORAL SOLUTION, 5 mg per 5 mL and DIAZEPAM INTENSOL™ Oral Solution (Concentrate), 5 mg per mL (Roxane Laboratories, Inc.): ADVERSE REACTIONS
- CLINICAL PHARMACOLOGY
- INDICATIONS AND USAGE
- ADVERSE REACTIONS
- DRUG ABUSE AND DEPENDENCE
- DOSAGE AND ADMINISTRATION
- HOW SUPPLIED
- Diseases/Conditions Related to DIAZEPAM ORAL SOLUTION, 5 mg per 5 mL and DIAZEPAM INTENSOL™ Oral Solution (Concentrate), 5 mg per mL (Roxane Laboratories, Inc.)
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Side effects most commonly reported were drowsiness, fatigue and ataxia. Infrequently encountered were confusion, constipation, depression, diplopia, dysarthria, headache, hypotension, incontinence, jaundice, changes in libido, nausea, changes in salivation, skin rash, slurred speech, tremor, urinary retention, vertigo and blurred vision. Paradoxical reactions such as acute hyperexcited states, anxiety, hallucinations, increased muscle spasticity, insomnia, rage, sleep disturbances and stimulation have been reported; should these occur, use of the drug should be discontinued.
Because of isolated reports of neutropenia and jaundice, periodic blood counts and liver function tests are advisable during long-term therapy. Minor changes in EEG patterns, usually low-voltage fast activity, have been observed in patients during and after diazepam therapy and are of no known significance.
- Drug Information Provided by National Library of Medicine (NLM).