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Drug Information for CYLERT (pemoline) CS-IV (Abbott Laboratories): DESCRIPTION
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CYLERT (pemoline) is a central nervous system stimulant. Pemoline is structurally dissimilar to the amphetamines and methylphenidate.
It is an oxazolidine compound and is chemically identified as 2-amino-5-phenyl-2-oxazolin-4-one. Pemoline has the following structural formula:
Pemoline is a white, tasteless, odorless powder, relatively insoluble (less than 1 mg/mL) in water, chloroform, ether, acetone, and benzene; its solubility in 95% ethyl alcohol is 2.2 mg/mL.
CYLERT (pemoline) is supplied as tablets containing 18.75 mg, 37.5 mg or 75 mg of pemoline for oral administration. CYLERT is also available as chewable tablets containing 37.5 mg of pemoline.
18.75 mg tablet: corn starch, gelatin, lactose, magnesium hydroxide, polyethylene glycol and talc.
37.5 mg tablet: corn starch, FD&C Yellow No. 6, gelatin, lactose, magnesium hydroxide, polyethylene glycol and talc.
37.5 mg chewable tablet: corn starch, FD&C Yellow No. 6, magnesium hydroxide, magnesium stearate, mannitol, polyethylene glycol, povidone, talc and artificial flavor.
75 mg tablet: corn starch, gelatin, iron oxide, lactose, magnesium hydroxide, polyethylene glycol and talc.
- Drug Information Provided by National Library of Medicine (NLM).