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Drug Information

Drug Information for Activella (Novo Nordisk): DESCRIPTION

Activella 1.0 mg/0.5 mg is a single tablet for oral administration containing 1 mg of estradiol and 0.5 mg of norethindrone acetate and the following excipients: lactose monohydrate, starch (corn), copovidone, talc, magnesium stearate, hypromellose and triacetin.
Activella 0.5 mg/0.1 mg is a single tablet for oral administration containing 0.5 mg of estradiol and 0.1 mg of norethindrone acetate and the following excipients: lactose monohydrate, starch (corn), hydroxypropylcellulose, talc, magnesium stearate, hypromellose and triacetin.
Estradiol (E₂) is a white or almost white crystalline powder. Its chemical name is estra-1, 3, 5 (10)-triene-3, 17ß-diol hemihydrate with the empirical formula of C₁₈H₂₄O₂, ½ H2O and a molecular weight of 281.4. The structural formula of E₂ is as follows:
Norethindrone acetate (NETA) is a white or yellowish-white crystalline powder. Its chemical name is 17ß-acetoxy-19-nor-17a-pregn-4-en-20-yn-3-one with the empirical formula of C₂₂H₂₈O₃ and molecular weight of 340.5. The structural formula of NETA is as follows:

Drug Information Provided by National Library of Medicine (NLM).

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