Disease Information for Zotepine (Zoleptil) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Motor restlessness
Akathisia
Athetosis
Choreoathetoid movement
Dystonia, acquired
Odd body posturing
Seizures
Tremor
Unable to sit still/restlessness
Diagnostic Test Results
EKG (ECG)
EKG/Drug induced QT prolongation (ECG)
EKG/Prolonged QT interval (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Convulsions (grand mal)
Drug induced Acute dystonia reaction
Drug Induced Choreoathetosis
Drug induced Movement disorder
Drug induced Orthostatic hypotension
Drug induced Prolonged Q-T interval
Neuroleptic malignant syndrome
Orthostatic hypotension syndrome
Orthostatic syncope Hypotension
Prolonged QT interval syndrome
Tardive dyskinesia syndrome
Urinary bladder retention
Disease Mechanism & Classification
Drugs
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Anti-Schizophrenia medication (example)
DRUG/Psychoactive/sedative drug (category)
DRUG/Blocks Serotonin/Dopamine receptors
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Zotepine (Zoleptil) admin, Britain-BNF/Zoleptil (Zotepine)
Treatment
Drug Dosage
DRUG/.$$$ Expensive medication
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose must be titrated to effect
DRUG/Dose TID Medication
DRUG/FDA application 2002
DRUG/Foreign license drug (non-USA)
DRUG/Intolerance in elderly/caution
DRUG/Oral medication (ex)
Definition

Antiserotonin and antidopamine receptor activity; New antipsychotic medication; action profile much like risperidone

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External Links Related to Zotepine (Zoleptil) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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