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- Disease Information
- Disease Comparison
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Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
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- Trauma
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Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
- Cardiovascular System
- Respiratory (Pulmonary) System
- Gastro-Intestinal (Digestive) System
- Urinary System
- Dermatologic System
- Endocrine System
- Immune System
- Musculoskeletal System
- Genital Reproductive System
- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Waterhouse-Friderichsen syndrome
- Clinical Manifestations
- Signs & Symptoms
- Capillary Refill Time/CRT Abnormal
- Falling blood pressure/progessive/signs
- Low Blood Pressure
- Signs of Poor Perfusion
- Bruising/Ecchymosis
- Fever and Rash
- Hemorrhagic rash
- Hemorrhagic/Confluent ecchymotic rash
- Non-pruritic rash
- Petechiae/Petechial rash
- Purpura
- Purpura, Generalized
- Rash
- Rash hand/foot areas
- Excessive/easy bruising tendency
- Renal Mass
- Kidney Mass
- Acute sepsis syndrome
- Collapse/Prostration
- Fever
- Fever Febrile Possible
- Flu-Like Syndrome
- High body temperature
- Mucous membrane pallor
- Toxic and Febrile Septic
- Disease Progression
- Course/Acute
- Course/Catastrophic presentation/onset
- Onset/Abrupt/Sudden
- Demographics & Risk Factors
- Population Group
- Child
- Population/Pediatrics population
- Sex & Age Groups
- Population/Child
- Population/Children/all
- Laboratory Tests
- Microbiology & Serology Findings
- Microlab/Niesseria meningococcus isolation/agent
- Abnormal Lab Findings (Non Measured)
- Acute inflammatory markers elevated (Lab)
- Fasting hypoglycemia (Lab)
- Abnormal Lab Findings - Decreased
- Bicarbonate, serum (Lab)
- Carbon Dioxide Total Content/CO2
- Cortisol (Lab)
- Glucose, blood (Lab)
- URINE Cortisol/Free Cortisol
- URINE Free Cortisol/24 Hour
- Diagnostic Test Results
- CT Scan
- CT Scan/Adrenal abnormality
- CT Scan/Adrenal mass
- CT Scan/Adrenal Mass Bilateral
- Image Scan/Unilateral Adrenal mass
- MRI/Adrenal mass/Abdomen
- MRI/Bilateral Adrenal Masses/abdomen
- X-RAY
- Xray/Adrenal calcifications/bilateral/KUB
- Associated Diseases & Rule outs
- Associated Disease & Complications
- Addison's disease
- Adrenal hemorrhage
- Adrenocortical insufficiency
- Coma/Unconscious
- Glucocorticoid Deficiency
- Hypoglycemia
- Hypotension
- Hypovolemia
- Hypovolemic shock
- Purpura fulminans
- Shock
- Disease Mechanism & Classification
- Class
- CLASS/Adrenal gland disorders (ex).
- CLASS/Endocrine gland (category)
- Pathophysiology
- Pathophysiology/Gangrene/skin/subcutaneous tissue
- Activated Protein C Resistance
- Pathophysiology/Activated protein C failure/deficit
- Pathophysiology/Intravasular coagulation process
- Pathophysiology/Spontaneous Coagulation
- Pathophysiology/Generalized Shwartzman reaction
- Process
- PROCESS/Complicating disorder (ex)
- PROCESS/Complicating/Specific process disorder (ex)
- PROCESS/Complication/primary failed organ/system (ex)
- PROCESS/Eponymic (category)
- Synonyms
- Synonym
- Purpura Fulminans (Waterhouse Friderichsen Syndrome), Waterhouse Friderichen, Waterhouse Friderichsen Syndrome, Waterhouse Friederichsen Syndrome, Synonym/Adrenal apoplexy with meningococcemia, Synonym/Adrenal hemorrhage syndrome, Synonym/Meningococcic adrenal hemorrhage
- Treatment
- Drug Therapy - Indication
- RX/Activated protein C (Xigris)
- RX/Corticosteroid (Cortisone)
- RX/Fluid/electrolytes intravenous
- Definition
-
A condition characterized by the abrupt onset of fever, petechiae, ARTHRALGIA, weakness, and myalgias followed by acute hemorrhagic necrosis of the adrenal glands and severe cardiovascular dysfunction; The syndrome is most often associated with meningococcal septicemia but may occur as a complication of sepsis caused by other organisms, including certain STREPTOCOCCUS species; This disorder may be associated with a prior history of SPLENECTOMY--------(From J Emerg Med 1998 Jul-Aug;16(4):643-7)--------------
(Edit)
- External Links Related to Waterhouse-Friderichsen syndrome
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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