Disease Information for Vincristine (Oncovin) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Bilateral Calf Pains
Leg cramps,nocturnal
Leg cramps/muscle spasm/pains
Motor and sensory neuropathy/Polyneuropathy signs
Laboratory Tests
Abnormal Lab Findings - Increased
ADH/Antidiuretic Hormone/Vasopressin/Oxytocin level (Lab)
Associated Diseases & Rule outs
Rule Outs
Guillain-Barre syndrome
Associated Disease & Complications
Anemia, aplastic
Drug induced Inappropriate ADH syndrome/SIADHS
Drug induced Peripheral neuropathy.
DRUG/Derivative Periwinkle (catharanthus rosea) anti-cancer agent
Fetal anomaly
Inappropriate ADH secretion syndrome
Peripheral neuropathy
Polyneuritis
Rhabdomyolysis
Toxic peripheral/polyneuropathy
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Antimitotics Chemotherapy
DRUG/Anti-tumor plant alkaloids (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/CHOP ChemoRx Protocol (Comb)
DRUG/COPE ChemoRX protocol (comb)
DRUG/Microtubule effect/mitotic arrest
DRUG/Mitotic inhibitor/spindle poison (ex)
DRUG/Teratogenic potential/effect (D plus )
DRUG/Vinca alkaloid chemotherapeutic drug
DRUG-Liver metabolism/bile excretion
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
22 Oxovincaleukoblastine, LCR, LEUROCRISTINE, oxovincaleukoblastine, VCR, Vincaleukoblastine 22 oxo, Vincristine, Vincristine (product), Vincristine (substance), VINCRISTINE PREPARATION, Vincrystine, Brand name/Oncovin (Vincristine)
Definition

Cancer chemotherapy drug; Vinca alkaloid class

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External Links Related to Vincristine (Oncovin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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