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Disease Information for Vinblastine (Velban) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Baldness/Alopecia

Hair loss

Non-scarring Alopecia/balding

Rash

Motor and sensory neuropathy/Polyneuropathy signs

Laboratory Tests

Abnormal Lab Findings - Decreased

Neutrophiles (Lab)

Associated Diseases & Rule outs

Rule Outs

Anxiety disorder/panic attacks

Associated Disease & Complications

Anemia, aplastic

Drug induced Baldness/Alopecia

Drug induced Peripheral neuropathy.

Drug induced Photosensitivity rash

Drug rash/Drug induced rash

DRUG/Derivative Periwinkle (catharanthus rosea) anti-cancer agent

Fetal anomaly

Peripheral neuropathy

Photosensitivity dermatitis

Phototoxicity

Polyneuritis

Raynaud's syndrome

Toxic peripheral/polyneuropathy

Polyneuropathy

Disease Mechanism & Classification

Drugs

DRUG/ABVD ChemoRX protocol (comb)

DRUG/Anti-tumor plant alkaloids (example)

DRUG/Chemotherapeutics/cancer drugs/etc (category)

DRUG/CMV ChemoRX protocol (comb)

DRUG/Microtubule effect/mitotic arrest

DRUG/Mitotic inhibitor/spindle poison (ex)

DRUG/M-VAC ChemoRx protocol (comb)

DRUG/Teratogenic potential/effect (D plus )

DRUG/Vinca alkaloid chemotherapeutic drug

DRUG-Liver metabolism/bile excretion

Process

PROCESS/Medication/Drug (CONFIRM dose/before treatment)

Synonyms

Synonym

admin, VBL, vinBLAStine, Vinblastine (product), Vinblastine (substance), VINBLASTINE PREPARATION, Vincaleucoblastine, VINCALEUKOBLASTINE, VLB, Brand name/Velban (Vinblastine), Brand name/Velbe (Vinblastine), Brand name/Velsar (Vinblastine)

Definition

Cancer chemotherapy drug; Vinca alkaloid class; this drug may be acceptable in limited chemo with Hodgkins in pregnany as doesn"t cross placental maternal fetal barrier

(Edit)

External Links Related to Vinblastine (Velban) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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