Disease Information for Verapamil (Calan/Isoptin) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Hypotension with Relative Bradycardia
Low Blood Pressure
Baldness/Alopecia
Hair loss
Non-scarring Alopecia/balding
Impotence, relative
Constipation in Elderly
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Abnormal Lab Findings - Increased
Digoxin serum level (Lab)
Prolactin (Lab)
Diagnostic Test Results
EKG (ECG)
EKG/Prolonged PR Interval (ECG)
EKG/Widened QRS pattern (ECG)
EKG/AV Nodal Block/Complete
EKG/Sinus bradycardia (ECG)
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Rule Outs
Digitalis toxicity/poisoning
Associated Disease & Complications
Brady-arrhythmia
Bradyarrhythmias
Calcium-channel blocker toxicity
Cardiac arrest
Cardiac conduction defects
Congestive heart failure
Constipation
Drug induced Constipation
Drug induced Impotence.
Esophagitis, reflux/GERD
Heart block, complete
Hypokalemia
Hypotension
Impotence/Erectile dysfunction disorder
Obstipation
Pulmonary edema
Sinus bradycardia
Disease Mechanism & Classification
Drugs
DRUG/Anti-anginal medication (example)
DRUG/Anti-arrhythmic medication (example)
DRUG/Antihypertensive medication (examples)
DRUG/Calcium-channel blocker meds (examples)
DRUG/Cardiovascular meds (examples)
DRUG/Class IV antiarrhythmic agent (example)
DRUG/Cytochrome p450 CYP3A Pathway
DRUG/Cytochrome p450 degradation/pharmacology (ex)
DRUG/Dangerous for kids (10Kg)/Very
DRUG/Important Acute care drugs (example)
DRUG/Non-dihydropyridine calcium channel blocker (ex)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Decreases Blood Pressure
TOXIN/Hypotension relative bradycardia
TOXIN/Inotropic decrease/shock (ex)
Synonyms
Synonym
alpha (3 ((2 (3,4 Dimethoxyphenyl)ethyl)methylamino)propyl) 3,4 dimethoxy alpha (1 methylethyl)benzeneacetonitrile, Benzeneacetonitrile alpha (3 ((2 (3,4 dimethoxyphenyl)ethyl)methylamino)propyl) 3,4 dimethoxy alpha (1 methylethyl), Iproveratril, verapamil, Verapamil (product), Verapamil (substance), VERAPAMIL PREPARATION, Brand name/Ampex (Verapamil), Brand name/Calan (Verapamil), Brand name/Chronovera (Verapamil), Brand name/Cordilox (Verapimil), Brand name/Covera (Verapamil), Brand name/Isoptin (Verapamil), Brand name/Tarka (Trandolapril/Verapamil), Brand name/Veradil (Verapamil), Brand name/Veralan (Verapamil), Brand Name/Verelan PM (Verapamil)
Treatment
Drug Therapy - Contraindication
RX/Digoxin (Lanoxin)
Drug Therapy - Indication
RX/Calcium chloride injection/infusion
RX/Calcium gluconate infusion
RX/Glucagon
Drug Dosage
DRUG/Dose 120 mgms (Unit/Pill/Capsule size)
DRUG/Dose 180 mgms (Unit/Pill/Capsule size)
DRUG/Dose 240 mgms (Unit/Pill/Capsule size)
DRUG/Dose 40 mgm (Unit/Pill/Capsule size)
DRUG/Dose 80 mgms (Unit/Pill/Capsule size)
DRUG/Dose Extended time release/XT/SA (example)
DRUG/Dose TID Medication
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
Definition

Calcium channel blocker medication; Cardiovascular drugs with selective and varied anti-vasospasm and hypertension and angina and anti-arrhythmia activity; Verapamil is used for atrial arryhthmia control and migraine prophylaxis as well as hypertension; Oral and parenteral drug

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External Links Related to Verapamil (Calan/Isoptin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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