Disease Information for Tumor lysis syndrome

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Clinical Manifestations
Signs & Symptoms
Acute bilateral Hand muscle spasms
Chvostek's sign
Cramping in Extremities
Muscle cramps/spasms
Trousseau's tourniquet sign positive
Truncal spasm/cramps
Spasms in Both Legs
Oliguria/Decreased urine output
Oliguria/sudden
Acutely ill patient/signs
Disease Progression
Course/Acute
Course/Acute on subacute
Course/Acute only
Demographics & Risk Factors
Established Disease Population
Patient/Cancer
Patient/Chemotherapy/cancer
Patient/Hodgkins disease
Patient/Lymphoma, malignant, non-Hodgkins
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Renal function abnormalities (Lab)
Abnormal Lab Findings - Decreased
Calcium, serum (Lab)
Abnormal Lab Findings - Increased
BUN/Blood urea nitrogen (Lab)
CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
Creatinine, serum (Lab)
Lactic Dehydrogenase (LDH LH) (Lab)
Magnesium (Lab)
Phosphate Serum (Lab)
Potassium, serum (Lab)
Uric acid, serum (Lab)
Diagnostic Test Results
Pathology
BX/Renal Kidney urate deposits
BX/Renal Kidney/Urate deposits
Associated Diseases & Rule outs
Associated Disease & Complications
Acute Renal Failure
Acute Tubulointerstitial Nephropathy
Azotemia/Acute
Cardiac arrest
Cardiac arrhythmias
Death/Unanticipated
Hyperkalemia
Hyperphosphatemia
Hyperuricemia
Hypocalcemia
Kidney stone/Uric acid/urates
Nephritis tubulointerstitial
Potassium administration/effect/toxicity
Tetany
Tumor lysis syndrome
Uric acid kidney stone formation
Cardiac death, sudden
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Renal function impairment
Pathophysiology/Renal manifestations/involvement
Pathophysiology/Secondary Renal Failure
Process
PROCESS/Iatrogenic (category)
PROCESS/Neoplastic (category)
PROCESS/Reference organ/system (category)
Synonyms
Synonym
Syndrome Tumor Lysis, Syndrome Tumour Lysis, Syndromes Tumor Lysis, Syndromes Tumour Lysis, Tumor lysis syndrome, Tumor lysis syndrome (disorder), Tumor Lysis Syndromes, TUMOUR LYSIS SYNDROME, Tumour Lysis Syndromes, DRUG Toxic drug combination syndrome
Treatment
Drug Therapy - Contraindication
RX/Potassium
Drug Therapy - Indication
RX/Alkalinization/urine
RX/Allopurinol (Zyloprim)
RX/Bicarbonate
RX/Forced diuresis
RX/Hydration/fluids/IV
RX/Rasburicase (Elitek Fasturtec)
Other Treatments
TX/Hemodialysis.
Definition

A syndrome resulting from cytotoxic therapy, occurring generally in aggressive, rapidly proliferating lymphoproliferative disorders. It is characterized by combinations of hyperuricemia, lactic acidosis, hyperkalemia, hyperphosphatemia and hypocalcemia.

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External Links Related to Tumor lysis syndrome
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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