Disease Information for Trifluoperazine (Stelazine) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Rash
Spontaneous ejaculation
Dry mouth/Mucous membranes
Motor restlessness
Akathisia
Athetosis
Choreoathetoid movement
Dystonia, acquired
Odd body posturing
Seizures
Shuffling 'magnetic' gait
Stupor/poor reponse to stimulus
Tremor
Unable to sit still/restlessness
Laboratory Tests
Abnormal Lab Findings - Decreased
Alkaline phosphatase, serum (Lab)
Neutrophiles (Lab)
Diagnostic Test Results
X-RAY
Xray/Radiopaque material/pills in gut/ABD
Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Convulsions (grand mal)
Drug induced Acute dystonia reaction
Drug Induced Choreoathetosis
Drug induced Inappropriate ADH syndrome/SIADHS
Drug induced Movement disorder
Drug induced Orthostatic hypotension
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Neuroleptic malignant syndrome
Orthostatic hypotension syndrome
Orthostatic syncope Hypotension
Parkinsonism, secondary
Photosensitivity dermatitis
Phototoxicity
Sedation/torpor induced
Tardive dyskinesia syndrome
Urinary bladder retention
Disease Mechanism & Classification
Drugs
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Anti-Schizophrenia medication (example)
DRUG/Phenothiazine class drug (example)
DRUG/Psychoactive/sedative drug (category)
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
10 (3 (4 Methyl 1 piperazinyl)propyl) 2 (trifluoromethyl) 10H phenothiazine, 10H Phenothiazine 10 (3 (4 methyl 1 piperazinyl)propyl) 2 (trifluoromethyl), admin, TFP, Trifluoperazine, Trifluoperazine (antipsychotic, Trifluoperazine (antipsychotic), Trifluoperazine (antipsychotic) (product), Trifluoperazine (antipsychotic) (substance), Trifluoperazine (nausea), Trifluoperazine (nausea) (see dh4 ), Trifluoperazine (nausea) (see dh4 ) (product), Trifluoperazine (nausea) (see dh4 ) (substance), Trifluoperazine (product), Trifluoperazine (substance), TRIFLUOPERAZINE PREPARATION, Trifluoroperazine, Trifluperazine, Brand name/Stelazine (Trifluoperazine)
Definition

Thorazine-like drug; class of neuroleptic drugs for anti-psychosis effect; oral preparation; causes sedation, tardive dyskinesia; basal ganglia effects; wide margin of safety

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External Links Related to Trifluoperazine (Stelazine) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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