Disease Information for Traztubumab (Herceptin) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Anemia
Bone marrow failure/exhaustion
Cardiomyopathy
Congestive heart failure
Drug induced Anemia.
Drug induced Cardiomyopathy/Cardiotoxicity.
Drug induced Myelosuppression.
Granulocytopenia/Neutropenia
Myelosuppression
Myocarditis, toxic
Thrombocytopenia
Thrombocytosis
Disease Mechanism & Classification
Drugs
DRUG/ Source rDNA Manufacture
DRUG/Biological response modifiers/chemoRX (example)
DRUG/Biologicals/serums/vaccines/blood products (cat)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/DNA Bioengineered Antibody (Imab/Umab/Omab)
DRUG/Genetically engineered/biological drug (example)
DRUG/Immune response modifier effect
DRUG/Monoclonal antibody medication/mab (example)
Pathophysiology
Pathophysiology/Myocardium Toxic Effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Traztubumab (Herceptin) admin, Brand name/Herceptin (Traztubumab), Synonym/Anti-HER2 breast cancer receptor antibody
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/1999 Approx. New drug (RX)
DRUG/Injectable medication (parenteral)
DRUG/Injectable preparation only
DRUG/Intravenous administraton RX
DRUG/Intravenous only RX
Definition

Recombinant DNA technology Bioengineered monoclonal antibody; Murine chimeric source; Anti HER2 receptor for

HER2 positive (hereditary) breast cancer; Usage

can cause cardiomyopathy

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External Links Related to Traztubumab (Herceptin) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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