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Disease Information for Transfusion reaction

Clinical Manifestations
Signs & Symptoms: Paroxysmal Shivering; Rigors/Shaking chills; Teeth Chattering; Uncontrollable Shaking
: Slate gray pigmentations
: Acute Back Pain; Back Pain; Backache
: Bilateral CVA/kidney tenderness; Dark urine
: Chills; Fever; Fever and Normal Sed Rate; Fever Febrile Possible; Flu-Like Syndrome; High body temperature; Infusion site/pain; Malaise; Total body pain/truncal/extremities
Disease Progression: Course/Chronic disorder; Course/Chronic only
Demographics & Risk Factors
Exposure Factors: Exposure/Specific blood donor
Population Group: Child; Population/Hospital patient; Population/Pediatrics population
Event, Activity, Behavioral & Seasonal Factors: Event/Metal detector alarm/airport/triggered; Lifestyle/Neglect/Poor/Negligent medical care situation
Sex & Age Groups: Population/Child; Population/Child-Infant Only; Population/Children/all
Laboratory Tests
Abnormal Lab Findings (Non Measured): Acute inflammatory markers elevated (Lab); Indirect Coombs Test Abnormal; Normocytic anemia; Normocytic/Normochromic Anemia (Lab); Renal function abnormalities (Lab)
Abnormal Lab Findings - Decreased: Platelet count (Lab)
Abnormal Lab Findings - Increased: Basophiles (Lab); Creatinine, serum (Lab); Direct Coombs test (Lab); Ferritin, serum (Lab); Indirect bilirubin (Lab); Iron, serum (Lab); Isohemagglutinin titers (Lab); Lactic Dehydrogenase (LDH LH) (Lab); Platelet Antibody Detection; Potassium, serum (Lab); Saturated iron binding capacity (Lab)
: URINE Hemoglobin; URINE Hemosiderin
Diagnostic Test Results
Pathology: Bone Marrow/Iron stores/increased; Bone Marrow/RES iron increased
: BX/Hepatic Iron Index Abnormal; BX/Liver biopsy/Increased liver iron stores
Isotope Scan: Isotope/Gallium scan/Bilateral increased renal pick-up
Associated Diseases & Rule outs
Rule Outs: Silicosis
Associated Disease & Complications: Acute Renal Failure; Acute Tubular Necrosis; Acute viremia; Anaphylaxis, generalized; Azotemia/Acute; Bacteremia Septicemia; Basophilia; Cardiomyopathy; Cytomegalic Virus; Diabetes mellitus; Disseminated intravascular coagulation; Drug Induced Infusion Reaction; Granulocytopenia/Neutropenia; Hemoglobinuria; Hemolysis anemia/acute/active; Hepatitis, viral; Hyperkalemia; Hypoparathyroidism/secondary; Immune deficiency , acquired (AIDS/HIV) disease/assn; Pulmonary edema/non-cardiogenic; Thrombocytopenia; Thrombocytopenia, autoimmune; Transfusion reaction; Transfusion reaction, hemolytic; Transfusion Related Acute Lung Injury; Urticaria/Drug Allergy; Urticaria/hives
: Iron Overload
Disease Mechanism & Classification
Class: CLASS/Erythrocyte disorder (ex); CLASS/Hematologic (category)
Pathophysiology: Pathophysiology/Hypersens type 2/Cytotoxic/IGM/IGG; Pathophysiology/Isoantibody/preformed alloantibodies/incr
: Pathophysiology/Hemolysis
Process: PROCESS/Metabolic/storage disorder (category); PROCESS/Storage disorder (ex)
: PROCESS/Transfusion reaction (ex)
Treatment
Drug Therapy - Indication: RX/Deferasirox (Exjade); RX/Deferoxamine (Desferal)
Definition: Be the first to add a definition for Transfusion reaction
External Links Related to Transfusion reaction: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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