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Disease Information for Toxoplasmosis, disseminated

Clinical Manifestations
Signs & Symptoms: Friction rub, pericardial
: Lymphadenopathy; Lymphadenopathy Systemic; Tender lymph nodes/systemic
: Seizures
: Dullness to percussion lung base; Localized decreased breath sounds; Localized dullness to percussion; Lung signs/abnormality
: Splenomegaly
: Acutely ill patient/signs; Fever; Fever Febrile Possible; Flu-Like Syndrome; High body temperature
: Visual acuity decreasing
Clinical Presentation & Variations: Fever in Immune Compromised; Presentation/Fever in Cellular Immune Defect
: AIDS with Altered Mental State; AIDS with Neurologic Manifestations; HIV AIDS with Cognitive Decline
Disease Progression: Course/Acute; Course/Acute only; Course/Potentially lethal/untreated; Lethal Potential
Demographics & Risk Factors
Exposure Factors: Exposure/Cat feces; Exposure/Cat/vector/reservoir; Exposure/Raw beef ingestion; Exposure/Raw hamburger/beef ingestion; Exposure/Raw meat/ game meat ingestion
Established Disease Population: Patient/AIDS established population
: Patient/Cellular immune defect; Patient/Immune compromised/Immune suppressed
Laboratory Tests
Microbiology & Serology Findings: Serum specific antibodies increased
: Microlab/Toxoplasmosis titer/serology
: Microlab/Toxoplasma gondii isolation
Abnormal Lab Findings (Non Measured): Acute inflammatory markers elevated (Lab)
Abnormal Lab Findings - Increased: CSF Cells
Diagnostic Test Results
Pathology: BX/Lymph node biopsy/Histiocytic blurring germinal centers
: BX/Liver biopsy/Granulomas in liver
X-RAY: Xray/Chest abnormal
: Xray/Chest/Lung fields/Abnormal; Xray/Hilar adenopathy, unilateral/Chest
Associated Diseases & Rule outs
Rule Outs: Cytomegalic mononucleosis; Infectious mononucleosis; Rubella; Toxoplasmosis, congenital
Associated Disease & Complications: AIDS Dementia; CNS disease/involvement; Convulsions (grand mal); Death Outcome; Glomerulonephritis, acute; Granulomatous liver/hepatitis syndrome; HIV/Eye Infection; Infectious myopathy; Myocarditis; Myocarditis, lymphocytic diffuse; Myocarditis, secondary; Neonatal thrombocytopenia; Nephritis, interstitial; Nephritis, non-allergic interstitial; Pericardial effusion; Pneumonia/Bronchopneumonia; Pneumonitis, secondary; Thrombocytopenia; Thrombocytopenia in Children; Toxoplasma meningoencephalitis; Toxoplasmosis, ocular
Disease Synergy - Causes: Synergy/Immune deficiency
Disease Mechanism & Classification
Specific Agent: AGENT/Crosses Placenta to Newborn; AGENT/Opportunistic infection prone (example); AGENT/Protozoan disease (ex); AGENT/Protozoan/plasmodia (category); AGENT/Severe Neonatal Infections; AGENT/Zoonosis disease (ex)
Class: CLASS/Systemic/no comment (category)
Pathophysiology: Pathophysiology/Granulomatous liver disease
Process: PROCESS/Complicating disorder (ex); PROCESS/Infection/agent specific (category)
Treatment
Drug Therapy - Indication: RX/Antibiotic; RX/Pyrimethamine (Daraprim); RX/Pyrimethamine/sulfadoxine (Fansidar); RX/Spiramycin (Rovamycin)
Definition: Be the first to add a definition for Toxoplasmosis, disseminated
External Links Related to Toxoplasmosis, disseminated: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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