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Disease Information for Thyrotoxic ophthalmopathy

Clinical Manifestations
Signs & Symptoms: Vertical Diplopia
: Staring Expression
: Tachycardia/Fast heart rate
: Moist, warm, smooth skin
: Enlarged thyroid gland; Thyromegaly/Symmetric enlargement
: Frequent bowel movements/not loose
: Warm/Extremities dry/warm to touch
: Chronic progressive ophthalmoplegia/Bilateral/CPEO; Tremor; Tremulousness
: Bilateral Eyelid Edema; Bloodshot eyes/Conjunctival injection; Chemosis/edema conjunctiva; Convergence difficulty; Difficulty Closing Eyelids; Difficulty Focusing Eyes; Diplopia Double vision; Double Image Vision Confirmed; Dry eyes/poor tearing; Dryness Conjunctiva; Eye Pain, Unilateral; Eye Pains, Bilateral; Eye symptoms/signs; Eyelid Retraction; Grainy/Gritty Eye Sensation; Infrequent blinking/Stellwag sign; Lagophthalmos/Unable to Close Eyelids; Lateral gaze weakness; Lid Lag; Periorbital edema/Puffy eyes; Prominent eyes; Proptosis,bilateral; Proptosis,unilateral; Ptosis (blepharoptosis); Ptosis, unilateral (blepharoptosis); Red Eyes Bilateral; Scleral Injection; Squint/sign; Stare/prominent eyes; Vision Loss; Wide Palpebral Fissures
Clinical Presentation & Variations: Presentation/Progressive Ophthalmoplegia
Demographics & Risk Factors
Established Disease Population: Patient/Graves disease/thyrotoxicosis; Patient/Thyrotoxicosis
Laboratory Tests
Abnormal Lab Findings - Increased: Anti-TSH receptor (TR/TRab/TBII/LATS)antibody (Lab)
: LATS/Long Acting Thyroid Stimulator (Lab); TSI (Thyroid stimulating immunoglobulin Assay (labs)
Diagnostic Test Results
Other Tests & Procedures: Intraocular Pressure increased; Ocular tonometry abnormal
Pathology: PATH/Lymphocytic infiltration/extraocular muscles; PATH/Orbital contents/lymphocytic infiltrate
Associated Diseases & Rule outs
Rule Outs: Cavernous sinus thrombosis
Associated Disease & Complications: Blindness; Esotropia; Exophthalmos; Ophthalmoplegia; Ophthalmoplegia/progressive/ext/chronic; Thyrotoxic ophthalmopathy; Vertical squint/strabismus; Visual acuity loss; Xerophthalmia
Disease Mechanism & Classification
Class: CLASS/Ophthalmology Specialty Population
: CLASS/Endocrine gland (category); CLASS/Thyroid gland disorder (ex)
: CLASS/Ophthalmology disorders
: CLASS/Extraocular muscle involvement/disorder (ex); CLASS/Eye involvement/disorder (ex); CLASS/Eyes/accessory (category)
Pathophysiology: Pathophysiology/Cytokine gene polymorphism; Pathophysiology/Genomic indentifiers (polymorphism/snip/mutations)
: Pathophysiology/Orbit inflammatory process
Process: PROCESS/Complicating disorder (ex); PROCESS/Complicating/Specific process disorder (ex); PROCESS/Endocrine/humoral disorders (category); PROCESS/Reference organ/system (category); PROCESS/Vegetative-Autonomic/Endocrine (category)
: PROCESS/Orbital inflammatory disease
Synonyms
Synonym: Exophthalmic thyrotoxicosis, Exophthalmos thyrotoxic, Thyrotoxic exophthalmos, Thyrotoxic exophthalmos (disorder), Synonym/Dysthyrotic ocular disorder, Synonym/Exophthalmos, endocrine
Treatment
Drug Therapy - Indication: RX/Selenium/trace metal; SX/Orbital decompression
Definition: Be the first to add a definition for Thyrotoxic ophthalmopathy
External Links Related to Thyrotoxic ophthalmopathy: Google; Wikipedia; Merck; Images; PubMed (National Library of Medicine); NGC (National Guideline Clearinghouse); Medscape (eMedicine); Harrison's Online (accessmedicine); NEJM (The New England Journal of Medicine)

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