Disease Information for Thyroid Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Paroxysmal Shivering
Rigors/Shaking chills
Teeth Chattering
Uncontrollable Shaking
Brief Blood pressure increase/sign:
High blood pressure/sign
Palpitations/Skipped beats
Pulse pressure/wide
Tachycardia/Fast heart rate
Fine skin changes/softer
Fingernails brittle/thinner/splitting
Appetite increased
Diarrhea/painless
Polyphagia
Weight loss good appetite
Hypertonia
Proximal lower extremity weakness
Action Tremor
Active reflexes
Exaggerated physiologic tremor (14Hz)
Excitement
Hyperreflexia/DTRs increased
Insomnia
Tremor
Tremor,fine
Tremulousness
Oligomenorrhea/Hypomenorrhea
Volatility/wild mood swings
Difficulty climbing stairs
Fever
Fever Febrile Possible
Flu-Like Syndrome
High body temperature
Increased energy
Restlessness/Anxiousness
Weight Loss
Mydriasis/wide pupils
Clinical Presentation & Variations
Presentation/Angina worse
Presentation/Diabetic Sudden uncontrolled Hyperglycemia
Presentation/Graves Disease spontaneous Resolved
Presentation/Uptake RAI Low Toxic patient High T4
Demographics & Risk Factors
Established Disease Population
Patient/Atrial fibrillation poor rate control
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Acute inflammatory markers elevated (Lab)
High T4, High T3, Low RAIU scan (Lab)
Abnormal Lab Findings - Decreased
TSH/Thyroid stimulating hormone (Lab)
Abnormal Lab Findings - Increased
Free T4 (Lab)
FTI/Free Thyroxin Index (Lab)
Glucose, blood (Lab)
T3 (RIA) serum level (Lab)
Thyroxin/T4 (Lab)
Diagnostic Test Results
Other Tests & Procedures
TEST/Basal metabolism rate increased/BMR
Isotope Scan
Isotope/RAI Uptake low/thyroid scan (I 123)
Isotope/RAI uptake/quantitative high thyroid (I 123)
CT Scan
CT/Dexa-Scan Bone density Abnormal
Associated Diseases & Rule outs
Rule Outs
Agoraphobia
Bipolar affective disorder
Neuroleptic malignant syndrome
Associated Disease & Complications
Atrial fibrillation
Drug induced Hyperglycemia
Drug induced Hypertension.
Drug induced tremor/movement disorder
Hyperglycemia
Hypermetabolic status
Hyperpyrexia
Hypertension
Hyperthermia
Hyperthyroid status
Male osteoporosis syndrome
Osteoporosis/osteopenia
Pathologic fractures
Supraventricular tachycardia
Tachyarrhythmia
Thyrotoxic periodic paralysis
Thyroxin toxicity/effect
Ventricular ectopy/VPBs
Metabolic Bone Disease
Disease Mechanism & Classification
Pathophysiology
Pathophysiology/Excess heat production
Pathophysiology/Metabolic rate increased
Pathophysiology/Mitochond oxidative phosp'n/uncoupled
Pathophysiology/Hyperkinetic heart status
Pathophysiology/Decrease TSH synthesis
Pathophysiology/Insulin resistant states
Pathophysiology/Osteoporosis Secondary
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Increases Heart Rate
Treatment
Drug Dosage
DRUG/Dose once daily (RX)
Definition

Natural thyroid hormone extract effect; oral preparation; may also refer to ANY thyroid supplement including thyroxin anf tri-iodothyroine (T3)

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External Links Related to Thyroid Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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