Disease Information for Thiotepa (Thioplex/Thiophosphoramide) Administration/Toxicity

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Associated Diseases & Rule outs
Associated Disease & Complications
Fetal anomaly
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Specialized usage (example)
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1,1',1'' Phosphinothioyldynetrisaziridine, 1,1',1 phosphinothioylidynetrisaziridine, 1,1',1'' Phosphinothioylidynetrisaziridine, Aziridine 1,1',1'' phosphinothioylidynetris, N,N' N'' Triethylenethiophosphoramide, N,N',N'' triethylenethiophosphoramide, TESPA, Thio Tepa, Thiofosfamide, Thiophosphamide, Thiophosphoramide, Thiotepa, Thiotepa (product), Thiotepa (substance), THIOTEPA PREPARATION, Triethylene thiophosphoramide, triethylenethiophosphoramide, tris(1 aziridinyl)phosphine sulfide, TSPA, Brand name/Immunex (Thiotepa), Brand name/Thioplex (Thiotepa), Synonym/Thiophosphoramide (Thiotepa) admin, Synonym/Thiotepa, Synonym/Triethylenethiophosphoramide/chem name
Definition

Primarily an Antineoplastic cancer chemotherapy drug; Alkylating agents interfere with methylation of DNA in mitosis, inhibits cell division; Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often; used in bladder cancer; parenteral preparation

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External Links Related to Thiotepa (Thioplex/Thiophosphoramide) Administration/Toxicity
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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