Disease Information for Thioridazine (Mellaril) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Rash
Impotence, relative
Dry mouth/Mucous membranes
Motor restlessness
Akathisia
Athetosis
Choreoathetoid movement
Dystonia, acquired
Odd body posturing
Seizures
Stupor/poor reponse to stimulus
Tremor
Unable to sit still/restlessness
Retinal pigmentation
Diagnostic Test Results
EKG (ECG)
EKG/Widened QRS pattern (ECG)
EKG/Drug induced QT prolongation (ECG)
EKG/Prolonged QT interval (ECG)
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Convulsions (grand mal)
Drug induced Acute dystonia reaction
Drug induced Arrhythmias
Drug Induced Choreoathetosis
Drug induced Impotence.
Drug induced Inappropriate ADH syndrome/SIADHS
Drug induced Movement disorder
Drug induced Orthostatic hypotension
Drug induced Photosensitivity rash
Drug induced Prolonged Q-T interval
Drug induced tremor/movement disorder
Drug rash/Drug induced rash
Ejaculation, retardation
Impotence/Erectile dysfunction disorder
Neuroleptic malignant syndrome
Orthostatic hypotension syndrome
Orthostatic syncope Hypotension
Parkinsonism, secondary
Photosensitivity dermatitis
Phototoxicity
Prolonged QT interval syndrome
Sedation/torpor induced
Tardive dyskinesia syndrome
Torsades de pointes/ventricular tachycardia
Urinary bladder retention
Ventricular fibrillation
Ventricular tachycardia/arrest
Disease Mechanism & Classification
Drugs
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Anti-Schizophrenia medication (example)
DRUG/D2 Receptor dopamine antagonist (Ex)
DRUG/Dangerous for kids (10Kg)/Very
DRUG/Older medication/little used
DRUG/Phenothiazine class drug (example)
DRUG/Psychoactive/sedative drug (category)
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
10H Phenothiazine 10 (2 (1 methyl 2 piperidinyl)ethyl) 2 (methylthio), Thioridazine, Thioridazine (product), Thioridazine (substance), THIORIDAZINE PREPARATION, Brand name/Mellaril (Thioridazine)
Treatment
Drug Therapy - Contraindication
RX/Pindolol (Visken)
RX/Propranolol (Inderal)
RX/Serotonin reuptake inhibitor
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose liquid/syrup/suspension form
DRUG/Dose TID Medication
DRUG/Oral medication (ex)
Definition

Thorazine-like drug; class of neuroleptic drugs for anti-psychosis effect; oral parenteral; causes sedation, tardive dyskinesia; basal ganglia effects; wide margin of safety

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External Links Related to Thioridazine (Mellaril) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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