Disease Information for Thalidomide (Thalomid) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Blood in stool
Dark/Black Melena Stool
Hematochezia/Blood per Rectum
Stool color/appearance abnormal
Associated Diseases & Rule outs
Associated Disease & Complications
Cleft Lip
Cleft lip/deformity
Cleft palate/deformity
Drug induced Peripheral neuropathy.
Fetal anomaly
Fetal damage/teratogenic effect
Limb deformities/anomalies
Peripheral neuropathy
Phocomelia
Polyneuritis
Toxic peripheral/polyneuropathy
Polyneuropathy
Hand anomalies
Disease Mechanism & Classification
Drugs
DRUG/Anti-angiogenesis medication
DRUG/Anti-leprosy antibiotic (example)
DRUG/Antimicrobic types of drug/classes (example)
DRUG/Immune modulator drug (ex)
DRUG/Teratogenic potential/effect (D plus )
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
DRUG/Fetal anomalies via father/sperm
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
( ) Thalidomide, (+) Thalidomide, 1H Isoindole 1,3(2H) dione 2 (2,6 dioxo 3 piperidinyl), 2 (2,6 Dioxo 3 piperidinyl) 1H isoindole 1,3(2H) dione, 2 6 Dioxo 3 phthalimidopiperidine, 2,6 Dioxo 3 phthalimidopiperidine, 3 Phthalimidoglutarimide, Alpha Phthalimidoglutarimide, N (2,6 Dioxo 3 piperidyl)phthalimide, N Phthaloylglutamimide, N Phthalylglutamic Acid Imide, Phthalimide N (2 6 dioxo 3 piperidyl) ( ), Phthalimide N (2 6 dioxo 3 piperidyl) (+), Sedalis, THAL, Thalidomide, Thalidomide chemical, Thalidomide chemical (substance), Thalidomide (product), Thalidomide (substance), THALIDOMIDE PREPARATION, Brand name/Thalomid (Thalidomide)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose Hour of sleep/HS medication
DRUG/Drug discontinued/TOXIC (RX)
Definition

Immunosuppressant novel drug; Anti-angiogenesis and VERY teratogenous drug used in leprosy and cancer chemotherapy including multiple myeloma; strict protocol control by manufacturer; oral preparation

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External Links Related to Thalidomide (Thalomid) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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