Disease Information for Tethered cord syndrome/congenital

Clinical Manifestations
Signs & Symptoms
Fecal Soiling in a Child
Spinal cord level lesion/signs
Back Pain Young Adult
Spine pain/vertebral skeletal pain
Disease Progression
Course/Chronic disorder
Course/Chronic only
Demographics & Risk Factors
Population Group
Population/Pediatrics population
Sex & Age Groups
Population/Child-Infant Only
Associated Diseases & Rule outs
Associated Disease & Complications
Spinal cord lesion/dysfunction
Disease Mechanism & Classification
CLASS/Pediatric disorders (ex)
CLASS/Neurologic (category)
CLASS/Spinal cord disorder (ex)
Pathophysiology/Dysraphia/congenital anomaly
PROCESS/Congenital/developmental (category)
PROCESS/Anomalies/Deformities/Malformations (EX)

Tethered Spinal Cord Syndrome; Congenital Tethered Cervical Spinal Cord Syndrome; Occult Spinal Dysraphism Sequence;

Tethered Cervical Spinal Cord Syndrome; Tethered Cord Malformation Sequence; Tethered Cord Syndrome

Tethered Spinal Cord Syndrome is a disorder characterized by progressive neurological deterioration that results from compression of the lowermost bundle of nerves of the spinal cord (cauda equina); It is most commonly associated with a defective closing of the neural tube (precursor of the spinal column) during embryonic development (Spina Bifida);

----------------------------------[nord website 2006]---------Tethered spinal cord syndrome is a neurological disorder caused by tissue attachments that limit the movement of the spinal cord within the spinal column; These attachments cause an abnormal stretching of the spinal cord; The course of the disorder is progressive; In children, symptoms may include lesions, hairy patches, dimples, or fatty tumors on the lower back; foot and spinal deformities; weakness in the legs; low back pain; scoliosis; and incontinence; Tethered spinal cord syndrome may go undiagnosed until adulthood, when sensory and motor problems and loss of bowel and bladder control emerge; This delayed presentation of symptoms is related to the degree of strain placed on the spinal cord over time; Tethered spinal cord syndrome appears to be the result of improper growth of the neural tube during fetal development, and is closely linked to spina bifida; Tethering may also develop after spinal cord injury and scar tissue can block the flow of fluids around the spinal cord; Fluid pressure may cause cysts to form in the spinal cord, a condition called syringomyelia; This can lead to additional loss of movement, feeling or the onset of pain or autonomic symptoms; In children, early surgery is recommended to prevent further neurological deterioration; If surgery is not advisable, spinal cord nerve roots may be cut to relieve pain; In adults, surgery to free (detether) the spinal cord can reduce the size and further development of cysts in the cord and may restore some function or alleviate other symptoms


External Links Related to Tethered cord syndrome/congenital
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)