Disease Information for Temozolomide (Temodar) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Bone marrow failure/exhaustion
Drug induced Myelosuppression.
Drug induced Neutropenia.
Drug induced Thrombocytopenia.
Fetal anomaly
Granulocytopenia/Neutropenia
Myelosuppression
Thrombocytopenia
Thrombocytosis
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Analog dacarbazine (DTIC)
DRUG/Anti-angiogenesis medication
DRUG/Anti-neoplastic medications (examples)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Oral Anti-cancer drug (ex)
DRUG/Readily enters CNS/CSF Blood-brain barrier
DRUG/Teratogenic potential/effect (D plus )
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
admin, Temozolomide (Temodar) admin, Brand name/Temodar/Temodal (Temozolomide)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/1999 Approx. New drug (RX)
DRUG/Oral medication (ex)
Definition

Primarily an Antineoplastic cancer chemotherapy drug; Alkylating agents interfere with methylation of DNA in mitosis, inhibits cell division; Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often

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External Links Related to Temozolomide (Temodar) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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