Disease Information for Tamoxifen (Nolvadex) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Hot Flushes
Morning sickness
Autonomic instability/Variable BP/HR
Hot flashes
Postmenopausal Bleeding
Postmenopausal Vaginal Bleeding
Laboratory Tests
Abnormal Lab Findings - Decreased
Apo Lp a (Little a) lipoprotein Level (Lab)
Estrogen, serum (Lab)
Abnormal Lab Findings - Increased
FSH/Follicle Stmulating Hormone/ICSH (Lab)
Thyroid Binding Globulin (Lab)
Diagnostic Test Results
Pathology
BX/Liver biopsy/Fatty change in liver tissue
Associated Diseases & Rule outs
Associated Disease & Complications
Adenocarcinoma, uterus
Atrophic vaginitis
Cataract
Fatty liver
Menopause/ovary disorder/seconday
Steatosis/Non-alcoholic steatosis hepatitis/NASH
Thromboembolic disease
Vasomotor instability
Disease Mechanism & Classification
Drugs
DRUG/Anti-estrogen drug (example)
DRUG/Anti-neoplastic medications (examples)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Hormonal agent/derivative medication (example)
DRUG/Hormonal agents/cancer chemotherapy (example)
DRUG/Oral Anti-cancer drug (ex)
DRUG/Synthetic estrogen receptor modifier/SERM (example)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
(Z) 2 (4(1,2 diphenyl 1 butenyl) phenoxyl) N,N dimethylethanamine, 1 p beta dimethylamino ethoxyphenyl trans 1,2 diphenylbut 1 ene, Ethanamine 2 (4 (1,2 diphenyl 1 butenyl)phenoxy) N,N dimethyl (Z), TAM, tamoxifen, Tamoxifen (product), Tamoxifen (substance), TAMOXIFEN PREPARATION, TMX, Brand name/Nolvadex (Tamoxifen), Brand name/Tamofen (Tamoxifen), Brand name/Tamone (Tamoxifen)
Treatment
Drug Dosage
DRUG/.$$$$ Very Expensive
DRUG/Dose 20 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Generic available
DRUG/Oral medication (ex)
Definition

Anti-estrogen medication; used in breast cancer as and adjuvant biologic response modifier and for prophylaxis; oral preparation

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External Links Related to Tamoxifen (Nolvadex) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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