Disease Information for Tacrolimus (Prograf/Protopic) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings - Increased
Platelet count (Lab)
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
Pathology
BX/Renal Glomerular intracapillary fibrin thrombi
Associated Diseases & Rule outs
Associated Disease & Complications
BK Virus Nephropathy/Transplants
Diabetes mellitus
Drug induced Myelosuppression.
Drug induced Thrombocytopenia.
Granulocytopenia/Neutropenia
Hemolytic-uremic syndrome
Lymphoma, non-Hodgkins type
Motor neuropathy
Myelosuppression
Osteoporosis/osteopenia
Thrombocytopenia
Thrombocytosis
Diabetes mellitus/non-insulin dep/type II
Disease Mechanism & Classification
Drugs
DRUG/Anti-Rejection Med/Organ transplant
DRUG/Blunts cytokine release/immune cells
DRUG/Calcineurin immunophilin inhibitor (ex)
DRUG/Calcium activated phosphatase/Calcineurin block
DRUG/Immune modulator drug (ex)
DRUG/Immune suppressant drug (example)
DRUG/Immune suppressive/agent research phase (example)
DRUG/Immunosuppressant Macrolide
DRUG/KKBP/Cyclophilin/Calcineurin Inhibitor
DRUG/Mast cell degranulation inhibitor medication (example)
DRUG/Neutrophile chemotaxis inhibited
DRUG/Pharmacology/P450 cytochrome enzyme induction
DRUG/Prevents transplant/allograft rejection
DRUG/T-cell inhibition effect
DRUG/Topical medication (example)
Pathophysiology
Pathophysiology/Osteoporosis Secondary
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
15,19 Epoxy 3H pyrido(2,1 c)(1,4)oxaazacyclotricosine 1,7,20,21(4H,23H) tetrone 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a hexadecahydro 5,19 dihydroxy 3 (2 (4 hydroxy 3 methoxycyclohexyl) 1 methylethenyl) 14,16 dimethoxy 4,10,12,18 tetramethyl 8 (2 p, Hexadecahydro 5,19 dihydroxy 3 (2 (4 hydroxy 3 methoxycyclohexyl) 1 methylethenyl) 14,16 dimethoxy 4,10,12,18 tetramethyl 8 (2 propenyl) 15,19 epoxy 3H pyrido(2,1 c)(1,4)oxaazacyclotricosine 1,7,20,21(4H,23H) tetrone, tacrolimus, Tacrolimus (product), Tacrolimus (skin), Tacrolimus (skin) (product), Tacrolimus (substance), TACROLIMUS PREPARATION, Brand name/FK506 (Tacrolimus), Brand Name/Hecoria (Tacrolimus), Brand name/Prograf (FK506/Tacrolimus), Synonym/FK506 immune-suppression drug
Treatment
Drug Therapy - Contraindication
RX/Non-steroidal anti-inflammatory drugs
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Bile high concentration
DRUG/Dose 1 mgm (Unit/Pill/Capsule size)
DRUG/Dose 5 mgm (Unit/Pill/Capsule size)
Definition

Immunomoduator drug; used for transplant rejection prevention and severe eczema; oral and topical preparation;

[skin cancer and lymphoma reported with unction]

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External Links Related to Tacrolimus (Prograf/Protopic) Administration/Toxicity
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Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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