Disease Information for Sulfonamides Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Photosensitivity/Sunsensitive skin
Rash
Goiter/thyroid enlargement/mass
Thyroid Mass
Paresthesias
Clinical Presentation & Variations
Presentation/Progressive Motor Sensory Polyneuropathy
Presentation/Pancreatitis Kids Recurrent
Demographics & Risk Factors
Established Disease Population
Patient/G6PD RBC hemolysis
Laboratory Tests
Abnormal Lab Findings - Decreased
Glucose, blood (Lab)
Platelet count (Lab)
Reduced glutathione, RBC (Lab)
Abnormal Lab Findings - Increased
Direct Coombs test (Lab)
Methemoglobin (Lab)
URINE Hematuria, microscopic
URINE Methemoglobin
URINE VMA
Diagnostic Test Results
Pathology
BX/Liver biopsy/Granulomas in liver
Associated Diseases & Rule outs
Associated Disease & Complications
Acute Tubulointerstitial Nephropathy
Agranulocytosis
Circulating coagulation inhibitor status
Dermatitis/Chronic rash
DRESS/Drug Hypersensitivity Syndrome
Drug induced Anemia.
Drug induced Hemolytic anemia.
Drug induced Hepatic toxicity
Drug induced Nephritis/Nephropathy
Drug induced Neutropenia.
Drug induced Pancreatitis
Drug induced Photosensitivity rash
Drug induced Rash/eruption/herbal
Drug induced Thrombocytopenia.
Drug rash/Drug induced rash
Eosinophilic pneumonia/prolonged
Erythema multiforme
Erythema nodosum
Glucose-6-PD Hemolytic crisis ('triggers')
Granulocytopenia/Neutropenia
Granulomatous liver/hepatitis syndrome
Hemolysis anemia/acute/active
Hypersensitivity angiitis
Methemoglobin inducing poisons/toxicity
Methemoglobinemia
Myocarditis, hypersensitivity/allergy
Nephritis tubulointerstitial
Nephritis, interstitial
Nephritis, secondary
Pancreatitis, acute
Peripheral neuropathy
Photosensitivity dermatitis
Phototoxicity
Polyneuritis
Porphyria, attack, acute intermittant
Pseudotumor cerebri
Stevens-Johnson syndrome
Sulfonamide allergy
Toxic epidermal necrolysis
Toxic erythema
Toxic hepatitis
Toxic nephritis/Chronic persistent
Toxic Nephritis/Nephropathy
Polyneuropathy
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Antimalarial medications (examples)
DRUG/Safe in pregnancy patient (B)
DRUG/Sulfa drug/antibiotic/congeners (example)
DRUG-Liver metabolism/bile excretion
Pathophysiology
Pathophysiology/Bilirubinemia/neonatal/kernicterus risk
Pathophysiology/Hemolysis
Pathophysiology/Granulomatous liver disease
Pathophysiology/Chronic intrinsic restrictive lung
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Characteristic Odor
TOXIN/Odor of rotten eggs
Definition

Sulfa drug antibiotics; high incidence of allergy reponse but excellent for UTI

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External Links Related to Sulfonamides Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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