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Disease Information for Sulfamethoxazole (Gantanol) Administration/Toxicity

Clinical Manifestations

Signs & Symptoms

Rash

Demographics & Risk Factors

Established Disease Population

Patient/G6PD RBC hemolysis

Laboratory Tests

Abnormal Lab Findings (Non Measured)

Heinz bodies RBC (Lab)

Heinz Body Prep/RBCs Positive

Associated Diseases & Rule outs

Associated Disease & Complications

Anemia, hemolytic, toxic

Drug induced Photosensitivity rash

Drug rash/Drug induced rash

Glucose-6-PD Hemolytic crisis ('triggers')

Nephritis tubulointerstitial

Photosensitivity dermatitis

Phototoxicity

Disease Mechanism & Classification

Drugs

DRUG/Antibiotic/antibacterial drug (example)

DRUG/Antibiotic/Antimicrobial drugs (category)

DRUG/Older medication/little used

DRUG/Sulfa drug/antibiotic/congeners (example)

Synonyms

Synonym

Benzenesulfonamide 4 amino N (5 methyl 3 isoxazolyl), Gamazole, Metoxal, Radonil, SMX, sulfamethoxazole, Sulfamethoxazole chemical, Sulfamethoxazole chemical (substance), Sulfamethoxazole (product), Sulfamethoxazole (substance), SULFAMETHOXAZOLE PREPARATION, Sulfamethylisoxazole, Sulfanilamide N' (5 methyl 3 isoxazolyl), Sulfisomezole, Sulphamethoxazole, Sulphamethoxazole chemical, Brand name/Gantanol (Sulfamethoxazole), Britain-BNF/Sulphamethoxazole (Sulfamethoxazole)

Treatment

Drug Dosage

DRUG/.1990 or before

DRUG/Dose 500 mgm (Unit/Pill/Capsule size)

DRUG/Dose BID Medication

DRUG/Half-life relatively long

DRUG/Oral medication (ex)

Definition

Sulfa drug antibiotic; oral dosage usual; high allergy incidence and mixed anti-bacterial spectrum but not usually a cidal drug; excellent urine concentration; used often for UTI

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External Links Related to Sulfamethoxazole (Gantanol) Administration/Toxicity

PubMed (National Library of Medicine)

NGC (National Guideline Clearinghouse)

Medscape (eMedicine)

Harrison's Online (accessmedicine)

NEJM (The New England Journal of Medicine)

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