Disease Information for Streptozocin (Zanosar) Administration/Toxicity

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Clinical Manifestations
Clinical Presentation & Variations
Presentation/Diabetic Sudden uncontrolled Hyperglycemia
Laboratory Tests
Abnormal Lab Findings - Decreased
Insulin level (Lab)
Potassium, serum (Lab)
Abnormal Lab Findings - Increased
Glucose, blood (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Diabetes mellitus
Drug induced Hypoglycemia
Fetal anomaly
Hypoglycemia
Hypokalemia
Lactic acidosis
Diabetes mellitus/non-insulin dep/type II
Disease Mechanism & Classification
Drugs
DRUG/Alkylating agents (example)
DRUG/Chemotherapeutics/cancer drugs/etc (category)
DRUG/Cytotoxic/chemotherapy medication (example)
DRUG/Nitrosurea alkylating agents (example)
DRUG/Teratogenic potential/effect (D plus )
DRUG-Liver metabolism/bile excretion
Pathophysiology
Pathophysiology/Pancreatic beta cell lysis
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
2 deoxy 2 (((methylnitrosamino) carbonyl)amino) D glucopyranose, 2 deoxy 2 (3 methyl 3 nitrosoureido) D glucopyranose, 2 Deoxy 2 (methylnitrosoamino)carbonyl)amino D glucose, D Glucose 2 deoxy 2 (((methylnitrosoamino)carbonyl)amino), streptozocin, Streptozocin (product), Streptozocin (substance), STREPTOZOCIN PREPARATION, Streptozotocin, Streptozotocine, STZ, SZC, SZN, Brand name/Zanosar (Streptozocin)
Definition

Primarily an Antineoplastic cancer chemotherapy drug. Speciality use only is recommended; a dangerous class of drugs with predictable bone marrow suppression often. Classed as an alkylating agent drug.

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External Links Related to Streptozocin (Zanosar) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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