Disease Information for Stibogluconate (Pentostam) Administration/Toxicity

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Clinical Manifestations
Clinical Presentation & Variations
Presentation/Pancreatitis Kids Recurrent
Associated Diseases & Rule outs
Associated Disease & Complications
Anemia
Anemia, hemolytic, toxic
Cardiomyopathy
Congestive heart failure
Drug induced Cardiomyopathy/Cardiotoxicity.
Drug induced Hemolytic anemia.
Drug induced Hepatic toxicity
Drug induced Pancreatitis
Hemolysis anemia/acute/active
Myocarditis, toxic
Toxic hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Anti-parasitic medications (examples)
DRUG/Anti-trypanoside antibiotic (example)
DRUG/Antiviral medication (example)
DRUG/Organic antimony medication (example)
DRUG/Tyrosine Phosphatase Inhibitor/effect
Pathophysiology
Pathophysiology/Myocardium Toxic Effect
Pathophysiology/Hemolytic process/effect
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Stibogluconate (Pentostam) admin, Brand name/Pentostam (Stibogluconate)
Treatment
Drug Therapy - Indication
RX/Dimercaprol (BAL)
Drug Dosage
DRUG/.1990 or before
Definition

Specialized antibiotic; used for kala-azar systemic leismaniasis; contains antimony; toxic to myocardium, liver, pancreas; WHO recommended for baghdad boil [10-20 days daily iv dose for us troops]; not approved by FDA;

intravenous and intramuscular preparation; heavier dose used and slower cure for cutaneous forms of leishmaniasis

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External Links Related to Stibogluconate (Pentostam) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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