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Disease Information for Status epilepticus
- Clinical Manifestations
- Signs & Symptoms
- Tachycardia/Fast heart rate
- Piloerection/goosebumps sign/skin
- Bowel/Stool Incontinence
- Stroke syndrome/signs
- Urine Incontinence
- Acutely ill patient/signs
- Compliance failures/Patient issues
- Fever
- Fever Febrile Possible
- Fever, high
- Flu-Like Syndrome
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- Clinical Presentation & Variations
- Presentation/High Temperature No Infection
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- Course/Acute
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- Course/Eventual terminal event/death possible
- Course/Potentially lethal/untreated
- Lethal Potential
- Demographics & Risk Factors
- Established Disease Population
- Patient/Epilepsy
- Occupational Factors
- Setting/Intensive/postop/cardiac care unit
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- Acute inflammatory markers elevated (Lab)
- CPK Extreme levels/MB fraction < 5" (Lab)
- Transaminase elevation (Lab)
- Very High CPK
- Abnormal Lab Findings - Decreased
- Lactic acid/Lactate (Lab)
- pO2, arterial blood (Lab)
- Abnormal Lab Findings - Increased
- Aldolase, serum (Lab)
- ALT (SGPT) (Alanine transferase) (Lab)
- Anion gap (Lab)
- Aspartamine aminotransferase (SGOT, AST) (Lab)
- AST (SGOT) (aspartamine transferase) (Lab)
- Carbon Dioxide Total Content/CO2
- CK-MM (Lab)
- CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
- Glucose, blood (Lab)
- Lactic acid/Lactate (Lab)
- Lactic Dehydrogenase (LDH LH) (Lab)
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- URINE Myoglobin
- Diagnostic Test Results
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- Cerebral vascular accident
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- Associated Disease & Complications
- Acidosis
- Acidosis, metabolic
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- Anal Incontinence
- Apnea
- Aspiration
- Death Outcome
- Death/Unanticipated
- Encephalopathy/postanoxic
- Hypercapnea Hypercarbia
- Hyperglycemia
- Hyperkalemia
- Hyperphosphatemia
- Hyperpyrexia
- Hyperthermia
- Hypoglycemia
- Hypoxemia
- Hypoxia, systemic
- Lactic acidosis
- Metabolic Acidosis with High Anion Gap
- Myoglobinuria
- Pneumonia, aspiration
- Pulmonary edema/non-cardiogenic
- Respiratory failure/Pulmonary insufficiency
- Rhabdomyolysis
- Seizure disorder (epilepsy)
- Status epilepticus
- Disease Mechanism & Classification
- Class
- CLASS/Neurologic (category)
- Pathophysiology
- Pathophysiology/Excess heat production
- Pathophysiology/Uncontrolled muscle contraction
- Pathophysiology/CSF Pressure Increased
- Pathophysiology/Epileptiform/epileptic disorder
- Pathophysiology/Lung Ventilation Neuromuscular
- Process
- PROCESS/Complicating disorder (ex)
- PROCESS/Vegetative-Autonomic/Endocrine (category)
- Treatment
- Drug Therapy - Indication
- RX/Anticonvulsants
- RX/Barbiturate
- RX/Diazepam (Valium)
- RX/Diazepam (Valium) injection (acute)
- RX/Lorazepam (Ativan)
- RX/Midazolam (Versed)
- RX/Pentobarbital (Nembutal)
- RX/Phenobarbital
- RX/Phenytoin
- RX/Sedation
- Other Treatments
- TX/General anesthesia/as treatment.
- TX/Intensive care management
- TX/Medical emergency
- TX/Restraint
- Definition
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A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes; The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction; Some are in COMA status with Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances; Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition ( EPILEPSIA PARTIALIS CONTINUA); Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity-----(From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)-----------
Common in ICU/CCU patients especially in hypoxic CNS injury, those with remote seizure history, and evident ocular movement abnormalities; treatment is usually Lorazepam or other Benzodiazepines; This can be a lethal disorder
(Edit)
- External Links Related to Status epilepticus
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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