Disease Information for Simvastin (Zocor) Administration/Toxicity

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Laboratory Tests
Abnormal Lab Findings - Increased
Coenzyme Q10 level
Associated Diseases & Rule outs
Associated Disease & Complications
Colchicine effect/toxicity
Drug induced Hepatic toxicity
Drug induced Myopathy.
Drug induced Rebound MI/Unstable angina
Rhabdomyolysis
Statin Myopathy
Toxic hepatitis
Disease Mechanism & Classification
Drugs
DRUG/Anti-cholesterol medications (examples)
DRUG/Antilipid drug (example)
DRUG/Cytochrome p450 degradation/pharmacology (ex)
DRUG/HMG-CoA reductase inhibitor/cholesterol (example)
DRUG/metabolized by CYP 3A pathway
DRUG/Statin Medication (ex)
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
Simvastin (Zocor) admin, Brand Name/Juvisync (Sitagliptin/DPP-4 and Simvastatin) Combination, Brand name/Simcor (Simvastatin-Niacin), Brand name/Vytorin (ezetimibe/simvastatin) combin., Brand name/Zocor (Simvastatin)
Treatment
Drug Therapy - Contraindication
RX/Itraconazole (Sporonox)
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose 20 mgm (Unit/Pill/Capsule size)
DRUG/Half-life 2 hrs
DRUG/Oral medication (ex)
-Pharmacology/Metabolized in liver
Definition

Lipid lowering drug. HMG Coenzyme A reductase inhibitor or so-called Statin drug. Oral preparation.

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External Links Related to Simvastin (Zocor) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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