Disease Information for Seborrheic keratosis

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Clinical Manifestations
Signs & Symptoms
Scaling/Skin finding
Scaly dermatitis/sign
Seborrheic keratosis/flare/Leser-Trelat sign
Thorax skin lesions
Vulva Dark Colored Lesion
Demographics & Risk Factors
Population Group
Aged Adult
Sex & Age Groups
Population/Adult Aged Only
Population/Adult/all
Population/Elderly Aged
Population/Seventies Adult
Diagnostic Test Results
Pathology
BX/Skin biopsy/Hyperkeratosis
Associated Diseases & Rule outs
Rule Outs
Actinic keratosis
Carcinoma, squamous, skin
Melanoma, malignant
Penile/genital warts
Associated Disease & Complications
Seborrheic keratosis
Disease Mechanism & Classification
Class
CLASS/Dermatologic/Subcutaneous (category)
Process
PROCESS/Reference organ/system (category)
Definition

Benign eccrine poromas that present as multiple oval, brown-to-black plaques, located mostly on the chest and back; The age of onset is usually in the fourth or fifth decade;

Common benign keratotic raised plagues benign tumors in older adults; Seborrheic keratoses usually are asymptomatic, but they can be an annoyance; Lesions can itch and rub or catch on clothing, thereby becoming inflamed; Patients are sometimes concerned that these enlarging lesions are malignant; Sometimes a person may have many seborrheic keratoses and not notice a dysplastic nevus or a malignant melanoma that develops among the seborrheic keratoses; spontaneous resolution does not occur; The sign of Lesser-Trélat is the association of multiple eruptive seborrheic keratoses with internal malignancy; adenocarcinoma, of the gastrointestinal tract; eruption of seborrheic keratoses may develop after an inflammatory dermatosis (egg, eczema, severe sunburn); typically have an appearance of being stuck on the skin surface ;color of the lesions can vary from pale brown with pink tones to dark brown or black; Differential diagnosis includes malignant melanoma, melanocytic nevus, verruca vulgaris, condyloma acuminatum, fibroepithelial polyp, epidermal nevus, actinic keratoses, pigmented basal cell carcinomas, and squamous cell carcinomas; lentigo maligna; acanthotic seborrheic keratoses resembles a melanocytic nevus, but the surface is less lustrous and the follicular orifices are plugged------(EMedicine)---------------

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External Links Related to Seborrheic keratosis
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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