Disease Information for Rifampin (Rifadin/Rimactane) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Red/erythema skin discoloration
Erythroderma
Pruritis Itching
Reddish-brown perspiration
Sweat/tears stain red-orange
Sputum red/heme negative
URINE Color Red
URINE Orange-red colored
Contact lenses stain red-orange
Clinical Presentation & Variations
Presentation/Warfarin Insensitivity Tolerance
Laboratory Tests
Abnormal Lab Findings (Non Measured)
URINE Color Orange
Abnormal Lab Findings - Decreased
Neutrophiles (Lab)
Abnormal Lab Findings - Increased
Platelet count (Lab)
Diagnostic Test Results
Other Tests & Procedures
Skin test anergy
Associated Diseases & Rule outs
Associated Disease & Complications
Acetamenophen (Tylenol) effect/toxicity
Acute Tubulointerstitial Nephropathy
Agranulocytosis
Anergic status
Bone marrow failure/exhaustion
Drug induced Hepatic toxicity
Drug Induced Infusion Reaction
Drug induced Myelosuppression.
Drug induced Nephritis/Nephropathy
Drug induced Neutropenia.
Drug induced Thrombocytopenia.
Erythema multiforme
Granulocytopenia/Neutropenia
Halothane exposure liver disease
Hemolytic anemia/autoimmune
INH Hepatitis
Myelosuppression
Nephritis tubulointerstitial
Nephritis, allergic interstitial acute
Nephritis, interstitial
Nephritis, secondary
Red Man Syndrome
Renal tubular acidosis, proximal
Thrombocytopenia
Thrombocytosis
Thrombotic thrombocytopenic purpura
Toxic hepatitis
Toxic nephritis/Chronic persistent
Toxic Nephritis/Nephropathy
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/antibacterial drug (example)
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Anti-leprosy antibiotic (example)
DRUG/Antituberculosis medication (example)
DRUG/Enterohepatic recirculation/elimination
DRUG/Enzyme induction effect/drug (ex)
DRUG/metabolized by CYP 3A pathway
DRUG/Oral contraceptive effect weakened
DRUG/Probably NOT safe/Pregnancy category C drug
DRUG-Liver metabolism/bile excretion
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Toxin
TOXIN/Enterohepatic recirculation/Use more charcoal
TOXIN/Hemodialysis failure occurs
Synonyms
Synonym
Benemycin, RIF, Rifampicin, Rifampicin product, RIFAMPIN, Rifampin (product), Rifampin (substance), RIFAMPIN PREPARATION, Rifamycin 3 (((4 methyl 1 piperazinyl)imino)methyl), Brand name/Rifadin (Rifampin), Brand name/Rifamate (combination), Brand name/Rifater (combination), Brand name/Rimactane (Rifampin), Brand name/Rofact (Rifampin)
Treatment
Drug Therapy - Contraindication
RX/Probenecid (Benemid)
Drug Therapy - Indication
RX/Antibiotic/Combinations
RX/Clofazimine (Lamprene)
Drug Dosage
DRUG/.$$$$ Very Expensive
DRUG/Bile high concentration
DRUG/Dose 150 mgms (Unit/Pill/Capsule size)
DRUG/Dose 300 mgm (Unit/Pill/Capsule size)
DRUG/Dose 600 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose liquid/syrup/suspension form
DRUG/Generic available
DRUG/Injectable medication (parenteral)
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
-Protein bound/drug
Definition

Antituberculosis antibiotic drug;used in combinations;other uses include methicillin resistant staphylococcus, listeria, and meningococcus, tularemia and brucellosis;parenteral and oral preparation;causes red colored urine and perpiration;Anti-leprosy antibiotic drug

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External Links Related to Rifampin (Rifadin/Rimactane) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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