Disease Information for Rhabdomyolysis

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Clinical Manifestations
Signs & Symptoms
Chest Pain
Exertional Muscle Pain
Local muscle tenderness
Muscle Pain
Muscle weakness
Muscles swelling
Myalgias
Pain in Extremities/Melalgias
Symmetrical muscle/pain, weakness
Tender or painful muscles/Myalgias
Weakness/Diffuse motor loss
Low Back Pain
Lumbar pain, acute
Bilateral CVA/kidney tenderness
Bilateral flank/kidney pain
Dark urine
URINE Color Red
Acute severe/total body pain
Weakness
Disease Progression
Course/Acute
Course/Acute on subacute
Course/Subacute
Demographics & Risk Factors
Established Disease Population
Patient/Cancer
Patient/Dehydrated
Patient/Diabetes mellitus
Laboratory Tests
Abnormal Lab Findings (Non Measured)
AST/SGOT above 1000 units/very high
CPK Extreme levels/MB fraction < 5" (Lab)
Transaminase elevation (Lab)
Very High CPK
Abnormal Lab Findings - Decreased
BUN/Creatinine ratio (Lab)
Calcium, serum (Lab)
Abnormal Lab Findings - Increased
Aldolase, serum (Lab)
ALT (SGPT) (Alanine transferase) (Lab)
Anion gap (Lab)
Aspartamine aminotransferase (SGOT, AST) (Lab)
AST (SGOT) (aspartamine transferase) (Lab)
CK-MM (Lab)
CPK/CK/Creatine kinase/Creatine phosphokinase (Lab)
Creatinine, serum (Lab)
Glucose, blood (Lab)
Lactic Dehydrogenase (LDH LH) (Lab)
Magnesium (Lab)
Myoglobin
Phosphate Serum (Lab)
Potassium, serum (Lab)
Uric acid, serum (Lab)
URINE Myoglobin
URINE Red blood cells
Associated Diseases & Rule outs
Associated Disease & Complications
Acidosis
Acidosis, metabolic
Acute anuria/renal failure
Acute Renal Failure
Azotemia in Children
Azotemia/Acute
Hyperglycemia
Hyperkalemia
Hypermagnesemia
Hyperphosphatemia
Hyperuricemia
Hypocalcemia
Metabolic Acidosis with High Anion Gap
Metabolic Myopathy
Myoglobinemia
Myoglobinuria
Myopathy
Potassium administration/effect/toxicity
Rhabdomyolysis
Volume depletion (intravascular)
Disease Mechanism & Classification
Class
CLASS/Muscle disorder (ex)
CLASS/Muscle/tendon/extremities (category)
CLASS/Striated muscle disorder (ex)
Pathophysiology
Pathophysiology/Blood volume/decrease/low
Pathophysiology/Metabolic myopathy (ex)
Pathophysiology/Renal intratubular obstruction process
Process
PROCESS/Non-hereditary metabolic disorder (ex)
PROCESS/Use/Age/atrophic disorder (category)
Treatment
Drug Therapy - Indication
RX/Alkalinization/urine
RX/Bicarbonate
RX/Fluid/electrolytes intravenous
RX/Mannitol (Osmotrol)
RX/Sodium bicarbonate infusion
Definition

Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.

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External Links Related to Rhabdomyolysis
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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