Disease Information for Retrolental fibroplasia

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Clinical Manifestations
Signs & Symptoms
Arterial narrowing/retina
Eye symptoms/signs
Leukocoria White pupil reflex
Poor Eye contact child/infant
Retinal pallor
Retinal vessel sclerosis/attenuation
Vitreous clouding on exam
Disease Progression
Course/Chronic disorder
Course/Subacute
Demographics & Risk Factors
Established Disease Population
Patient/Primature infant status
Population Group
Child
Infant
Population/Pediatrics population
Sex & Age Groups
Population/Child
Population/Child-Infant Only
Population/Children/all
Population/Infant
Associated Diseases & Rule outs
Associated Disease & Complications
Blindness
Blindness in Children
Congenital eye disease/eye anomalies
Myopia
Retina detachment
Retinal hemorrhage
Vitreous hemorrhage
Disease Mechanism & Classification
Class
CLASS/Pediatric disorders (ex)
CLASS/Eye involvement/disorder (ex)
CLASS/Eyes/accessory (category)
CLASS/Retina involvement/disorder (ex)
CLASS/Vitreous disorder (ex)
Process
PROCESS/Biochemical (category)
PROCESS/Reference organ/system (category)
Treatment
Drug Therapy - Indication
RX/Vitamin E
Definition

A bilateral retinopathy occurring in premature infants treated with excessively high concentrations of oxygen, characterized by vascular dilatation, proliferation, and tortuosity, edema, and retinal detachment, with ultimate conversion of the retina into a fibrous mass that can be seen as a dense retrolental membrane. Usually growth of the eye is arrested and may result in microophthalmia, and blindness may occur. (Dorland, 27th ed)

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External Links Related to Retrolental fibroplasia
Google
Wikipedia
Merck
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PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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