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- Disease Information
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Disease Processes ▼
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Major Organs-Systems ▼
- Systemic
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Disease Information for Rasmussen's syndrome/encephalitis
- Clinical Manifestations
- Signs & Symptoms
- Adolescent
- Unilateral symptoms/signs/findings
- Weakness/one arm
- Aphasia
- Delayed speech/language development
- Delirium
- Delirium/Agitated delirium
- Dysphasia
- Frontal lobe signs
- Hemiplegic Gait
- Infant Seizures
- Irritability/short tempered
- Mental Deficiency Child
- Mental Slowing Deteriation
- Motor slowing
- Myoclonus/Myoclonic jerks on exam
- Seizures/Children/recurrent
- Delayed speech development/impediment
- Chronic Fatigue
- Typical Clinical Presentation
- Presentation/Epilepsy/several types/focal motor/child
- Clinical Presentation & Variations
- Presentation/Child Hemiplegia Encephalopathy Dementia Seizures
- Disease Progression
- Course/Progressive/slowly chronic illness
- Onset/5-15 years old
- Demographics & Risk Factors
- Population Group
- Child
- Population/Pediatrics population
- Sex & Age Groups
- Population/Adolescent
- Population/Child
- Population/Child-Infant Only
- Population/Children/all
- Laboratory Tests
- Abnormal Lab Findings (Non Measured)
- CSF abnormal
- CSF Colloidal gold curve abnormal
- Abnormal Lab Findings - Increased
- CSF Cells
- CSF Leukocytes
- Diagnostic Test Results
- Other Tests & Procedures
- Lumbar puncture/Increased CSF pressure/LP test
- Pathology
- BX/Brain biopsy/Abnormal
- PATH/Brain abnormal
- PATH/Brain focal encephalopathy
- PATH/Brain Neuronophagia microglial nodules motor frontal
- PATH/Brain/Cellular infiltrate/chronic
- PATH/Brain/Pyramidal cell loss
- PATH/Encephalomalacia/inflammatory frontal lobe
- Electrodiagnosis
- EEG/Periodic lateralizing epileptiform discharge/PLED
- EEG/Seizure activity abnormality
- CT Scan
- CT Scan/Head Brain Abnormality
- MRI/Head Brain Abnormal
- SPECT Head Scan/Thallium 201/abnormal
- MRI/Chest abnormal
- Associated Diseases & Rule outs
- Rule Outs
- Cortical dysplasia
- MELAS/Encephalopathy
- Russian Encephalitis
- Tuberous Sclerosis
- Associated Disease & Complications
- Cerebral hemisphere/involvement lesion
- CNS disease/involvement
- Encephalitis
- Encephalopathy/CNS effect
- Epilepsy
- Epilepsy partialis continua
- Focal motor seizure
- Hemiplegia
- Meningitis, chronic
- Mental retardation
- Neurodevelopmental disorders
- Partial complex seizure
- Seizure disorder (epilepsy)
- Status epilepticus
- Todds paralysis/postictal
- Disease Mechanism & Classification
- Specific Agent
- AGENT/Unclassified/unknown microbe (category)
- Class
- CLASS/Pediatric disorders (ex)
- CLASS/Primary organ/system disorder (ex)
- CLASS/Brain/CNS disorder (ex)
- CLASS/Frontal lobe involvement/disorder (ex)
- CLASS/Neurologic (category)
- CLASS/Temporal lobe disorder (ex)
- Pathophysiology
- Pathophysiology/Autoimmune GluR3 glutamate receptors/CNS
- Pathophysiology/Epileptic encephalopathy
- Pathophysiology/Indolent hemispheric encephalitis
- Process
- PROCESS/Autoimmune disorder (ex)
- PROCESS/Idiopathic/unclassified/unknown (category)
- PROCESS/INCIDENCE/Esoteric disease (example)
- PROCESS/INCIDENCE/Extremely rare disease
- PROCESS/Post-infectious disorder (ex)
- Synonyms
- Synonym
- ENCEPH RASMUSSEN, Encephalitis Rasmussen, RASMUSSEN ENCEPH, Rasmussen encephalitis, Rasmussen syndrome, Rasmussen syndrome (disorder), Rasmussen's Syndrome, Synonym/Chronic encephalitis and epilepsy, Synonym/Chronic focal encephalitis (Rasmussen), Synonym/Chronic hemispheric encephalitis syndrome, Synonym/Chronic localized/focal encephalitis, Synonym/Epilepsy-Hemiplegia-mental retardation, Synonym/Rasmussen's disease, Synonym/Rasmussen's encephalitis/hemiplegia, Synonym/RE (Rasmussen Encephalitis]
- Treatment
- Drug Therapy - Indication
- RX/Corticosteroid (Cortisone)
- RX/Gamma globulin (intravenous, high dose)
- SX/Hemispherectomy
- Other Treatments
- TX/Ketogenic diet
- TX/Plasmapheresis/exchange.
- Definition
-
Rare chronic mildly progressive encephalitis with epilepsy; hemispheric limit involves frontal lobe and maybe temporal;
focal cellular infiltrate; mental retarded regression; onset always before age 10; hemispherectomy has helped but as post viral post-infectious autoimmune disorder IVIG infusion or plasmaphoresis has helped; seizures are hard to treat; surgery seems to halt progression; signs are unilateral but cellular infiltrate may be bilateral; 5 yr course variable; possible post flu or measles onset; residuals occur but aphasia often clears
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Rasmussen"s encephalitis; Rasmussen"s disease ; Rasmussen"s syndrome; An extremely rare, progressive, central nervous system disorder, characterized by frequent and severe seizures, loss of motor skills, hemiparesis, inflammation of the brain, and mental deterioration; This disorder occurs almost exclusively in children under the age of 10;
----------------[whonamedit_com 2005]----------
(Edit)
- External Links Related to Rasmussen's syndrome/encephalitis
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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