Disease Information for Quinine Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Rash
Rash on legs/ankles
Acute Diarrhea
Diarrhea
Diarrhea/painless
Bitter Taste
Vertigo
Hallucination/visual
Cherry red spot/retinal sign
Color blindness acquired/dimming
Acute Hearing Loss
Hearing problems
Sound distortion
Sudden deafness
Tinnitus
Tinnitus in Elderly
Vertigo in Children
Vertigo in Elderly
Demographics & Risk Factors
Established Disease Population
Patient/G6PD RBC hemolysis
Laboratory Tests
Abnormal Lab Findings - Decreased
Platelet count (Lab)
Diagnostic Test Results
EKG (ECG)
EKG/Widened QRS pattern (ECG)
EKG/Drug induced QT prolongation (ECG)
EKG/Prolonged QT interval (ECG)
EKG/AV Nodal Block/Complete
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Acute gastroenteritis
Anemia
Anemia, hemolytic, toxic
Blindness
Bradyarrhythmias
Cardiac arrhythmias
Cardiac conduction defects
Cinchonism/Salicylism syndrome
Congestive heart failure
Deafness
Deafness, sensorineural
Dermatitis, exfoliative, generalized
Disseminated intravascular coagulation
Drug induced Anemia.
Drug induced Arrhythmias
Drug induced Diarrhea.
Drug induced Hemolytic anemia.
Drug induced Neutropenia.
Drug induced Photosensitivity rash
Drug induced Prolonged Q-T interval
Drug induced Thrombocytopenia.
Drug rash/Drug induced rash
Erythema multiforme
Glucose-6-PD Hemolytic crisis ('triggers')
Granulocytopenia/Neutropenia
Heart block, complete
Hemolysis anemia/acute/active
Hemolytic anemia/autoimmune
Hemolytic-uremic syndrome
Lichen planus
Livedo reticularis
Photosensitivity dermatitis
Phototoxicity
Pulmonary edema
Torsades de pointes/ventricular tachycardia
Toxic amblyopia syndrome
Ventricular fibrillation
Ventricular tachycardia/arrest
Lichenoid Dermatitis
Lichenoid Mucositis
Deafness Acquired
Disease Synergy - Causes
Triggers of mastocytosis crises/abdominal pain
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Antimalarial medications (examples)
DRUG/Anti-parasitic medications (examples)
Pathophysiology
PROCESS/Thrombotic Microangiopathy
Pathophysiology/Thrombotic microangiopathy/TMA
Pathophysiology/Hemolysis
Pathophysiology/Hemolytic process/effect
Pathophysiology/CNS-Systemic Vertigo
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
( ) Quinine, Cinchonan 9 ol 6' methoxy (8alpha 9R), QUIN, quinine, Quinine (product), Quinine (substance), QUININE PREPARATION, Brand name/Qualaquin (Quinine Sulfate)
Treatment
Drug Therapy - Contraindication
RX/Rifampin (Rifadin)
RX/Warfarin (Coumadin)
Drug Dosage
DRUG/.1990 or before
DRUG/Dose 200 mgms (Unit/Pill/Capsule size)
DRUG/Dose 324 mgms (Unit/Pill/Capsule size)
DRUG/Generic available
DRUG/Oral medication (ex)
Definition

Anti-malarial antibiotic drug; anti-arrhythmia drug; old natural occurring medication used for nocturnal leg cramps; oral and parenteral preparation; causes cinchonism with deafness and tinnitus)

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External Links Related to Quinine Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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