Disease Information for Quinacrine (Mepacrine) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Hyperpigmented patches/sun exposed areas
Yellow skin discoloration
Yellow/brown skin on exam
Oral pigmentation lesions
Yellow skin/white sclera
Confusion/Disoriented
Delirium
Delirium/Agitated delirium
Diagnostic Test Results
Pathology
PATH/Black pigmented cartilage/connective tissue/Ochronosis
PATH/Black/bluish pigment connective tissue
Associated Diseases & Rule outs
Rule Outs
Neurosis/psychoneurosis
Psoriasis
Associated Disease & Complications
Acute hepatic necrosis/yellow atrophy
Dermatitis, exfoliative, generalized
Drug induced Delirium/Confusion
Drug induced Exfoliative dermatitis.
Drug induced Pigment changes.
Drug induced Psychosis/toxic psychosis.
Psychosis
Secondary Psychosis/Symptomatic
Toxic psychosis
Disease Mechanism & Classification
Drugs
DRUG/Antibiotic/Antimicrobial drugs (category)
DRUG/Anti-parasitic medications (examples)
DRUG/Prion suppression ? in animals
DRUG/Teratogenic/OBGYN Class X/Pregnancy DANGER
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
1 4 Pentanediamine N4 (6 chloro 2 methoxy 9 acridinyl) N1 N1 diethyl, admin, Atebrin, Mepacrine, Mepacrine (product), Mepacrine (substance), QUINACRINE, Quinacrine (substance), QUINACRINE PREPARATION, TOX, Brand name/Atabrine (Quinacrine), Brand name/Mepacrine (Quinacrine)TOXIC
Treatment
Drug Dosage
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose TID Medication
DRUG/Drug discontinued/TOXIC (RX)
DRUG/Foreign license drug (non-USA)
Definition

Anti-malarial antibiotic drug; little used as TOXIC; Also an antiparasite antibiotic drug

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External Links Related to Quinacrine (Mepacrine) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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