Disease Information for Quetiapine (Seroquel) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Dizzy on Standing/Giddy Response
Orthostatic drop in blood pressure
Dry mouth/Mucous membranes
Motor restlessness
Akathisia
Athetosis
Choreoathetoid movement
Dystonia, acquired
Odd body posturing
Seizures
Stupor/poor reponse to stimulus
Tremor
Unable to sit still/restlessness
Diagnostic Test Results
EKG (ECG)
EKG/Drug induced QT prolongation (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Cardiac arrhythmias
Cataract
Convulsions (grand mal)
Drug induced Acute dystonia reaction
Drug Induced Choreoathetosis
Drug induced Movement disorder
Drug induced Orthostatic hypotension
Neuroleptic malignant syndrome
Orthostatic hypotension syndrome
Orthostatic syncope Hypotension
Sedation/torpor induced
Tardive dyskinesia syndrome
Urinary bladder retention
Disease Mechanism & Classification
Drugs
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Anti-Schizophrenia medication (example)
DRUG/Atypical anti-psychotic neuroleptic drugs
DRUG/Phenothiazine class drug (example)
DRUG/Psychoactive/sedative drug (category)
DRUG/Blocks Serotonin/Dopamine receptors
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
admin, Quetiapine (Seroquel), Brand name/Seroquel (Quetiapine)
Treatment
Drug Dosage
DRUG/.$$$$$ Most Expensive
DRUG/Dose 100 mgm (Unit/Pill/Capsule size)
DRUG/Dose 25 mgm (Unit/Pill/Capsule size)
DRUG/Dose BID Medication
DRUG/Dose must be titrated to effect
DRUG/Dose TID Medication
DRUG/Oral medication (ex)
Definition

Thorazine-like drug; class of neuroleptic drugs for anti-psychosis effect; oral and parenteral drug; causes sedation, tardive dyskinesia; basal ganglia effects; wide margin of safety

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External Links Related to Quetiapine (Seroquel) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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