Disease Information for Pyridoxine excess/megadose

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Clinical Manifestations
Signs & Symptoms
Pain in Extremities/Melalgias
Absent knee reflexes
Ankle reflexes absent
Ataxia/Posterior columns
Glove/stocking hypesthesia
Loss of pain of temperature sensation
Loss position sense/postural sense
Romberg sign positive
Seizures
Sensory Ataxia
Staggering Gait
Symmetric Polyneuropathy
Unable to tandem walk/straight line
Falling
Megavitamin ingestion/habits
Laboratory Tests
Abnormal Lab Findings - Increased
Pyridoxine/Vitamin B6 (Lab)
Associated Diseases & Rule outs
Associated Disease & Complications
Ataxic neuropathy
Convulsions (grand mal)
Drug induced Peripheral neuropathy.
Peripheral neuropathy
Polyneuritis
Sensory neuropathy
Toxic peripheral/polyneuropathy
Ataxia Disorder
Polyneuropathy
Disease Mechanism & Classification
Class
CLASS/Foods/flavoring/herbs/benign items (category)
Drugs
DRUG/Anti-anemia/hematinic medication (example)
DRUG/Vitamin/minerals supplements (example)
DRUG-Supplement Group (example)
Pathophysiology/Hypervitaminosis
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Treatment
Drug Therapy - Contraindication
RX/Pyridoxine (Vitamin B6)
Definition
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External Links Related to Pyridoxine excess/megadose
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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