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- Disease Information
- Disease Comparison
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Disease Processes ▼
- Auto Immune
- Vascular-Arteriosclerosis
- Biochemical
- Congenital-developmental
- Deficiency
- Degenrative-Necrosis
- Electromagnetic-Physics
- Eponymic
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Major Organs-Systems ▼
- Systemic
- Pediatric
- Nervous & Sensory System (Neurology)
- Cardiovascular System
- Respiratory (Pulmonary) System
- Gastro-Intestinal (Digestive) System
- Urinary System
- Dermatologic System
- Endocrine System
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- Musculoskeletal System
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- Hematopoietic System (Hematology)
- Lymphatic System
- Tissue/Cells/Organelles
Disease Information for Pyoderma gangrenosa
- Clinical Manifestations
- Signs & Symptoms
- Facial ulceration/ulcers
- Red/erythema skin discoloration
- Cutaneous granulomatous ulceration/signs
- Cutaneous ulcer/Skin ulcer
- Cutaneous ulcers/boggy red irregular borders
- Cutaneous ulcers/necrotic purulent base/center
- Cutaneous ulcers/purulent base
- Cutaneous ulcers/under-cut border
- Delayed/poor wound healing
- Encrusting Skin Lesions
- Erythroderma
- Hyperpathia phenomenon (venipuncture inf)
- Leg Ulcers in Children
- Leg Ulcers in Elderly
- Necrotic Insect/Spider Bite/Central Ulcer
- Painful skin ulcer
- Red/blue skin ulcers/irregular borders/multiple
- Residual Scars lower extremity lesions
- Skin pathergy/needle stick/sterile pustule/erythema
- Skin Ulcer with Eschar
- Sores/weeping sores skin/extremity
- Ulcer/skin 'punched out' type
- Chronically ill patient/signs
- Clinical Presentation & Variations
- Presentation/Painful Leg Ulcer Chronic
- Disease Progression
- Course/Chronic disorder
- Course/Chronic only
- Course/Persistent/symptoms possible
- Course/Progressive
- Course/Relentless
- Demographics & Risk Factors
- Established Disease Population
- Patient/Inflammatory Bowel Disease
- Patient/Ulcerative colitis
- Laboratory Tests
- Microbiology & Serology Findings
- Microlab/Cutaneous ulcer/lesion culture abnormal
- Microlab/Skin scraping lesions/bacteria on stain
- Diagnostic Test Results
- Pathology
- BX/Skin biopsy/Abnormal
- BX/Skin biopsy/Dermis infiltrate/neutrophiles
- BX/Skin/Acute Inflammation Polys
- PATH/Tissue neutrophiles/microabscessing/necrosis
- Associated Diseases & Rule outs
- Rule Outs
- Anthrax
- Cellulitis
- Cutaneous Blastomycosis
- Decubitus ulcer/Bedsores
- Impetigo/Pyoderm
- Spider bite, Brown Recluse
- Sporotrichosis
- Associated Disease & Complications
- Cutaneous Infection
- Decubitus ulcer/Bedsores
- PAPA syndrome
- Pyoderma gangrenosa
- Ulceroglandular syndrome
- Granulomatous Dermatitis
- Leg ulcers
- Disease Mechanism & Classification
- Class
- CLASS/Cellular Immune System Disorder (ex)
- CLASS/Dermatologic/Subcutaneous (category)
- CLASS/Skin disorder (ex)
- Pathophysiology
- Pathophysiology/Granulomatous skin areas/lesions
- Pathophysiology/Ulcer/Dermatologic disorder (ex)
- Pathophysiology/Activated cellular immunopathology
- Pathophysiology/Immune physiology/defective
- Pathophysiology/Immune/cellular system disorder (ex)
- Process
- PROCESS/Allergy/collagen/autoimmune (category)
- PROCESS/Allergy/inflammatory/granulomatous disorder (ex).
- PROCESS/Infected organ/abscess (category)
- PROCESS/Reference organ/system (category)
- Synonyms
- Synonym
- gangrenosum pyoderma, Pyoderma gangenosum, PYODERMA GANGRENOSA, Pyoderma gangrenosum, Pyoderma gangrenosum (disorder), PYODERMA GANGRENOUS, Synonym/Bullous Pyoderma Gangenosa, Synonym/Necrotizing subcutaneous infection, Synonym/Pustular Pyoderma Gangenosa, Synonym/Vegetative Pyoderma Gangenosa
- Treatment
- Drug Therapy - Indication
- RX/Anakinra (Kineret)
- RX/Ciclosporine Cyclosporin (Sandimmune)
- RX/Corticosteroid (Cortisone)
- RX/Infliximab (Remicade)
- RX/Mycophenolate mofetil (MMF)
- RX/Tacrolimus (Prograf)
- RX/Thalidomide (Thalomid)
- Surgical Procedures or Treatments
- SX/Biopsy
- Surgical Procedures or Treatments
- SX/Biopsy
- Other Treatments
- TX/Plasmapheresis/exchange.
- Definition
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An idiopathic, rapidly evolving, and severely debilitating disease occurring most commonly in association with chronic ulcerative colitis. It is characterized by the presence of boggy, purplish ulcers with undermined borders, appearing mostly on the legs. The majority of cases are in people between 40 and 60 years old. Its etiology is unknown.
(Edit)
- External Links Related to Pyoderma gangrenosa
- Wikipedia
- Merck
- Images
- PubMed (National Library of Medicine)
- NGC (National Guideline Clearinghouse)
- Medscape (eMedicine)
- Harrison's Online (accessmedicine)
- NEJM (The New England Journal of Medicine)
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