Disease Information for Promethazine (Phenergan) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Rash
Dry mouth/Mucous membranes
Seizures
Dry eyes/poor tearing
Dryness Conjunctiva
Grainy/Gritty Eye Sensation
Diagnostic Test Results
Isotope Scan
Isotope/RAI uptake/quantitative high thyroid (I 123)
Associated Diseases & Rule outs
Associated Disease & Complications
Convulsions (grand mal)
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Photosensitivity dermatitis
Phototoxicity
Xerophthalmia
Disease Mechanism & Classification
Drugs
DRUG/Antiemetic medication (examples)
DRUG/Antihistamine medication (examples)
DRUG/Anti-vertigo/Motion sickness medication (ex)
DRUG/Psychoactive/sedative drug (category)
DRUG/Lowers seizure threshold
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
10H Phenothiazine 10 ethanamine N N alpha trimethyl, Diprazinum, Proazamine, Prometazin, PROMETHAZINE, Promethazine (dup) (substance), Promethazine (nausea), Promethazine (nausea) (see c8i ), Promethazine (nausea) (see c8i ) (product), Promethazine (nausea) (see c8i ) (substance), Promethazine (product), Promethazine (substance), PROMETHAZINE PREPARATION, Promethazine product, Brand name/Phenergan (Promethazine)
Treatment
Drug Dosage
DRUG/Dose 25 mgm (Unit/Pill/Capsule size)
DRUG/Dose 50 mgm (Unit/Pill/Capsule size)
DRUG/Dose liquid/syrup/suspension form
DRUG/Dose QID Medication
DRUG/Dose Rectal enema/suppository available
DRUG/Generic available
DRUG/Injectable medication (parenteral)
DRUG/Intramuscular injection RX
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
Definition

Antihistamine medication; older medication; causes drowsiness, delirium, EKG QRS prolonged on overdose; Some anticholinergic effects; some sedative psychoactive drug effect; used for sedation and narcotic potentiation and antemetic effect injection, suppository, oral preparations;

lowers seizure threhold

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External Links Related to Promethazine (Phenergan) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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