Disease Information for Promazine (Sparine) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Tachycardia/Fast heart rate
Rash
Athetosis
Choreoathetoid movement
Dystonia, acquired
Odd body posturing
Tremor
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Diagnostic Test Results
EKG (ECG)
EKG/Widened QRS pattern (ECG)
EKG/Changes/abnormalities (ECG)
Associated Diseases & Rule outs
Associated Disease & Complications
Agranulocytosis
Drug induced Acute dystonia reaction
Drug Induced Choreoathetosis
Drug induced Movement disorder
Drug induced Neutropenia.
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Granulocytopenia/Neutropenia
Neuroleptic malignant syndrome
Parkinsonism, secondary
Photosensitivity dermatitis
Phototoxicity
Disease Mechanism & Classification
Drugs
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Dopamine antagonist (example)
DRUG/Phenothiazine class drug (example)
DRUG/Psychoactive/sedative drug (category)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
10H Phenothiazine 10 propanamine N N dimethyl, Promazine, Promazine (product), Promazine (substance), PROMAZINE PREPARATION, Brand name/Sparine (Promazine)
Treatment
Drug Dosage
DRUG/Dose 12.5 mgms (Unit/Pill/Capsule size)
DRUG/Dose Multi-dose Vial preparation
Definition

Thorazine-like drug; class of neuroleptic drugs for anti-psychosis effect; oral parenteral; causes sedation, tardive dyskinesia; basal ganglia effects; wide margin of safety

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External Links Related to Promazine (Sparine) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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