Disease Information for Prochlorperazine (Compazine) Administration/Toxicity

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Clinical Manifestations
Signs & Symptoms
Low Blood Pressure
Rash
Athetosis
Choreoathetoid movement
Dystonia
Dystonia, acquired
Nystagmus
Odd body posturing
Tremor
Low body temperature
True Vertigo Sign Confirmed
Laboratory Tests
Abnormal Lab Findings (Non Measured)
Hyperprolactinemia
Abnormal Lab Findings - Decreased
Neutrophiles (Lab)
Abnormal Lab Findings - Increased
Prolactin (Lab)
Diagnostic Test Results
X-RAY
Xray/Radiopaque material/pills in gut/ABD
Associated Diseases & Rule outs
Associated Disease & Complications
Drug induced Acute dystonia reaction
Drug Induced Choreoathetosis
Drug induced Movement disorder
Drug induced Neutropenia.
Drug induced Photosensitivity rash
Drug rash/Drug induced rash
Granulocytopenia/Neutropenia
Hypotension
Hypothermia
Neuroleptic malignant syndrome
Parkinsonism, secondary
Parkinsons disease
Photosensitivity dermatitis
Phototoxicity
Secondary Dystonia
Disease Mechanism & Classification
Drugs
DRUG/Antiemetic medication (examples)
DRUG/Antipsychotic/neuroleptic drug (example)
DRUG/Anti-vertigo/Motion sickness medication (ex)
DRUG/Dopamine antagonist (example)
DRUG/Phenothiazine class drug (example)
DRUG/Psychoactive/sedative drug (category)
Process
PROCESS/Medication/Drug (CONFIRM dose/before treatment)
Synonyms
Synonym
10H Phenothiazine 2 chloro 10 (3 (4 methyl 1 piperazinyl)propyl), 2 Chloro 10 (3 (1 methyl 4 piperazinyl)propyl) phenothiazine, PCPZ, PROCHLORPERAZINE, Prochlorperazine (antipsych), Prochlorperazine (antipsych) (see dhe ), Prochlorperazine (antipsych) (see dhe ) (product), Prochlorperazine (antipsych) (see dhe ) (substance), Prochlorperazine (nausea), Prochlorperazine (nausea) (product), Prochlorperazine (nausea) (substance), Prochlorperazine (product), Prochlorperazine (substance), PROCHLORPERAZINE PREPARATION, RP 6140, SKF 4657, Brand name/Compazine (Prochlorperazine), Brand name/Stemetil (Prochlorperazine)
Treatment
Drug Dosage
DRUG/Dose 10 mgm (Unit/Pill/Capsule size)
DRUG/Dose 25 mgm (Unit/Pill/Capsule size)
DRUG/Dose 5 mgm (Unit/Pill/Capsule size)
DRUG/Dose Extended time release/XT/SA (example)
DRUG/Dose Multi-dose Vial preparation
DRUG/Dose QID Medication
DRUG/Dose Rectal enema/suppository available
DRUG/Dose TID Medication
DRUG/Generic available
DRUG/Injectable medication (parenteral)
DRUG/Intramuscular injection RX
DRUG/Intravenous administraton RX
DRUG/IV requires lesser dose/Caution
DRUG/Oral medication (ex)
Definition

Anti-emetic drug principally; however, Thorazine-like drug; oral and parenteral,rectal preparations;causes sedation, basal ganglia effects;wide margin of safety

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External Links Related to Prochlorperazine (Compazine) Administration/Toxicity
Google
Wikipedia
Merck
Images
PubMed (National Library of Medicine)
NGC (National Guideline Clearinghouse)
Medscape (eMedicine)
Harrison's Online (accessmedicine)
NEJM (The New England Journal of Medicine)
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